Cefxone Injection IM 1 gm 1 Vial works by interfering with certain processes that help the bacteria to grow and increase in number.
Side effects
Major & minor side effects for Cefxone Injection IM 1 gm 1 Vial

Black or tarry stools Severe

Chest pain Severe

Fever severe

Difficulty or painful urination severe

Sore throat severe

Diarrhea severe

Abdominal pain severe

Dizziness severe

Swelling of face, lips, eyelids, tongue, hands and feet severe

Acid or sour stomach severe

Change in taste rare

Excessive air or gas in stomach rare

Uses of Cefxone Injection IM 1 gm 1 Vial
What is it prescribed for?

Bacterial Meningitis
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord. This infection may be caused by Streptococcus pneumoniae or Neisseria meningitidis.

Bacterial Septicemia
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.

Gonococcal Infection
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

Urinary Tract Infection
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of infections of the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

Pneumonia
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

Bone and joint infections
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of bone and joint infections such as septic arthritis and osteomyelitis caused by Staphylococci and Streptococci species.

Skin and structure Infection
Cefxone Injection IM 1 gm 1 Vial is used in the treatment of Skin and structure infections such as cellulitis, wound infection and cutaneous abscesses caused by Streptococcus pyogenes and Staphylococcus aureus.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine occurs rapidly after intravenous and intramuscular routes of administration of the dose.

Duration of Effect
The effect of this medicine lasts for an average duration of 24 hours.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit forming tendency has been reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Cefxone Injection IM 1 gm 1 Vial or any other Beta-lactam antibiotics such as penicillins or cephalosporins.

Lidocaine
Cefxone Injection IM 1 gm 1 Vial is contraindicated for use if Lidocaine is used as a solvent for intravenous injection. Lidocaine can be used as a solvent for the intramuscular route of injection for this medicine, despite contraindications.

Calcium-containing products
Cefxone Injection IM 1 gm 1 Vial is contraindicated in neonates who are on calcium-containing intravenous solutions or infusions such as parenteral nutrition because of the risk of precipitation of Cefxone Injection IM 1 gm 1 Vial and calcium.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

General Warnings

Allergy
This medicine is not recommended for use in patients with a known history of allergy to Cefxone Injection IM 1 gm 1 Vial or Beta-lactam Antibiotics such as penicillins and cephalosporins.

Hemolytic anemia
An immune mediated hemolytic anemia has been reported in patients receiving Cefxone Injection IM 1 gm 1 Vial and other cephalosporins. Report any unusual symptoms to the doctor immediately. Your doctor may advise you to discontinue the medicine if you develop hemolytic anemia until the exact cause is determined.

Prothrombin time
Alterations in prothrombin time (a test used to check for bleeding problems) have been reported in patients receiving Cefxone Injection IM 1 gm 1 Vial . Regular monitoring of prothrombin time may be necessary for some patients. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Drug-resistance
Usage of Cefxone Injection IM 1 gm 1 Vial without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Patients with impaired kidney or liver function
This medicine should be used with caution in patients with kidney or liver diseases due to the increased risk of severe adverse effects. The dose of this medicine should not exceed 2 g/day for such patients.

Clostridium difficile-associated Diarrhea
This medicine is not recommended for use if you experience severe diarrhea after receiving Cefxone Injection IM 1 gm 1 Vial . Antibiotic therapy may cause an imbalance in the normal microbial flora in the large intestine; this may promote the growth of bacteria called Clostridium difficile, leading to severe diarrhea. Your doctor may prescribe a safer alternative based on your clinical condition.

Use in neonates
is not recommended in patients less than 28 days of age.

Dosage

Missed Dose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Amikacin Moderate

Ethinyl Estradiol Moderate

Cholera Vaccine Severe

Cyclosporine Moderate

Disease interactions

Moderate
This medicine may cause diarrhea, abdominal pain and blood in stools in some cases. This risk is especially higher in patients with a history of gastrointestinal diseases. Drink an adequate amount of water to prevent dehydration. Report any such symptoms to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Moderate
This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures since it may worsen the patient’s condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

This medicine is usually administered in the hospital by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report any unusual symptoms or side effects to the doctor immediately. Report any allergies to antibiotics to the doctor prior to using this medicine.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

References

dailymed.nlm.nih.gov –
ceftriaxone- ceftriaxone sodium injection, powder, for solution [Internet] [Internet].
Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dd1be9e-74cc-48e8-bf02-f34a78d80fda
[cited 25 August 2019].
N/A

Practo.com –
Ceftriaxone – Uses, Dosage, Side Effects, Price, Composition | Practo [Internet].
Available from: https://www.practo.com/medicine-info/ceftriaxone-51-api
[cited 25 August 2019].
11 Jan 2018

https://medlineplus.gov –
Ceftriaxone Injection [Internet].
Available from: https://medlineplus.gov/druginfo/meds/a685032.html
[cited 25 August 2019].
11 September 2019