COLDOFER ORANGE FLAVOUR Syrup 60ml Allschoolabs -

Description

INTRODUCTION
COLDOFER ORANGE FLAVOUR SYRUP is a combination of Phenylephrine and Chlorpheniramine which belongs to the group of medicines called Nasal decongestants and Antihistamines respectively. It is used to relieve nasal and sinus congestion, allergic symptoms of the nose or throat due to upper respiratory tract allergies, sinus pain and headache.
Also, it is used adjunctly with antibacterials to treat sinusitis (inflammation of the tissue lining the sinuses), tonsillitis (inflammation of the tonsils) and otitis media (middle ear infection).
Before giving COLDOFER ORANGE FLAVOUR SYRUP to your child, inform child?s doctor if your child has kidney, liver or heart problems, diabetes, fits or severely raised blood pressure.
COLDOFER ORANGE FLAVOUR SYRUP is not recommended for use in pregnant or breast-feeding women and elderly patients as it is used only in children.
The most common side effects of COLDOFER ORANGE FLAVOUR SYRUP are nausea, vomiting, dry mouth, dizziness and tiredness. Consult your child?s doctor if any of the side effects worsen.
USES OF COLDOFER ORANGE FLAVOUR SYRUP

Relieves nasal and sinus congestion

Relieves allergic symptoms of the nose or throat due to upper respiratory tract allergies

Relieves sinus pain and headache

Used adjunctly with antibacterials to treat sinusitis, tonsillitis and otitis media

HOW COLDOFER ORANGE FLAVOUR SYRUP WORKS
COLDOFER ORANGE FLAVOUR SYRUP relieves cold symptoms where phenylephrine decreases nasal congestion by acting on ?1-adrenergic receptors in the small vessels of the nasal mucosa to produce constriction, resulting in decreased swelling and increased drainage of the sinus cavities and chlorpheniramine binds to the?histamine?H1 receptor and blocks its action, resulting in temporary relief of the negative?symptoms (runny nose, sneezing, watery and itchy eyes)?brought on by?histamine.
DIRECTIONS FOR USE
Give COLDOFER ORANGE FLAVOUR SYRUP to your child as advised by the physician. Shake well before use. Use a measuring cup to properly measure the dose. Your child?s doctor will decide the correct dose and duration of COLDOFER ORANGE FLAVOUR SYRUP for your child depending upon child?s age, body weight and disease condition.
SIDE EFFECTS OF COLDOFER ORANGE FLAVOUR SYRUP

COMMON

Drowsiness and sedation

Disturbance in concentrating, un-coordination, dizziness, headache

Blurred vision

Nausea or vomiting

Dry mouth

Tiredness

RARE

Increased heart rate, palpitation

Fear, anxiety, restlessness

Tremor, weakness

Painful urination

Insomnia

Hallucinations, convulsions
Stop giving COLDOFER ORANGE FLAVOUR SYRUP to your child and contact doctor immediately if your child experiences any of the following side effects:
Develop rash, hives, itching, red or swollen or blistered or peeling skin; wheezing, tightness in the chest or throat, trouble breathing, swallowing or talking, unusual hoarseness or swelling of the mouth, face lips, tongue or throat

HOW TO MANAGE SIDE EFFECTS
Headache:
Apply hot or cold-water bag on your child?s head. Advise your child to take rest in a quiet room. Massage child?s scalp or head with mild pressure for relieving effect. Consult child?s doctor if the symptom does not improve.
Nausea and vomiting:
Follow simple meal plan for your child while administering COLDOFER ORANGE FLAVOUR SYRUP. Avoid giving foods that are oily, fried or spicy foods. Do not let your child to lie down or sleep immediately after eating. Consult child?s doctor if the symptom does not improve.
Dry mouth:
Tell your child to sip water regularly and other sugar free liquids. Tell your child not to use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Consult child?s doctor if the symptom does not improve.
WARNING & PRECAUTIONS

PREGNANCY
COLDOFER ORANGE FLAVOUR SYRUP is not recommended for use in pregnant women as it is used only in children. Consult your doctor for advice.
BREASTFEEDING
COLDOFER ORANGE FLAVOUR SYRUP is not recommended for use in breast-feeding women as it is used only in children. Consult your doctor for advice.
DRIVING AND USING MACHINES
Do not let your child ride bicycles or drive other vehicles or operate any tools if your child experiences dizziness, drowsiness and sedation after taking COLDOFER ORANGE FLAVOUR SYRUP.
ALCOHOL
Avoid medicines containing alcohol during administration of COLDOFER ORANGE FLAVOUR SYRUP.
KIDNEY
COLDOFER ORANGE FLAVOUR SYRUP should be used with caution in children with kidney failure. Consult your child?s doctor for advice before administration of COLDOFER ORANGE FLAVOUR SYRUP to your child.
LIVER
COLDOFER ORANGE FLAVOUR SYRUP should be used with caution in children with liver impairment. Consult your child?s doctor for advice before administration of COLDOFER ORANGE FLAVOUR SYRUP to your child.
ALLERGY
Talk to your child?s doctor if your child is allergic to Phenylephrine, Chlorpheniramine or any other ingredients of this medicine.
HEART DISEASE
COLDOFER ORANGE FLAVOUR SYRUP is not recommended for use in children with severely high blood pressure. COLDOFER ORANGE FLAVOUR SYRUP should be used with caution in patients with any other cardiovascular problems. Consult your child?s doctor for advice before administration of COLDOFER ORANGE FLAVOUR SYRUP to your child.
OTHERS
COLDOFER ORANGE FLAVOUR SYRUP is not recommended for use if your child:
Has phaeochromocytoma (rare tumours that start in the inner part of the adrenal gland)

Peripheral or mesenteric vascular thrombosis (blood clots usually in legs or major veins (one or more) that drain blood from the intestine
Before giving COLDOFER ORANGE FLAVOUR SYRUP to your child, inform your physician if your child:
Has diabetes

Has overactive thyroid

Has closed angle glaucoma

Has history of fits
Use in pediatrics:
COLDOFER ORANGE FLAVOUR SYRUP should be used with caution in children from 1 month to 12 years of age. Consult your child?s doctor for advice before administration of COLDOFER ORANGE FLAVOUR SYRUP.
Use in geriatrics:
COLDOFER ORANGE FLAVOUR SYRUP is not recommended for use in elderly patients as it is used only in children. Consult your doctor for advice.
INTERACTIONS
A. Drug ? Drug interactions:
Before giving COLDOFER ORANGE FLAVOUR SYRUP to your child, inform to child?s doctor if your child is taking or receiving any of the following medicines:?
Medicines used to treat depression (Ex. selegiline, phenelzine, amitriptyline)

Ephedrine (used to treat low blood pressure)

Phenytoin (used to treat epilepsy)

Digoxin (used to treat irregular heartbeat)

Medicines used to treat anxiety and induce sleep (Ex. alprazolam, chlordiazepoxide, clonazepam)
Overdosage:
If you or anyone else accidentally take too much of COLDOFER ORANGE FLAVOUR SYRUP, contact your doctor immediately or visit a nearby hospital. Overdosage symptoms of COLDOFER ORANGE FLAVOUR SYRUP includes extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations and possibly seizures.
SYNOPSIS

Drug :?? Phenylephrine, Chlorpheniramine

Pharmacological Category :?? Nasal decongestant, Antihistamine

Therapeutic Indication :?? Relieves nasal and sinus congestion, allergic symptoms, sinus pain, sinusitis, tonsillitis and otitis media (in addition with antibiotics)

Dosage Forms :?? Capsule, Tablet, Syrup, Oral drops

MORE INFORMATION

Keep COLDOFER ORANGE FLAVOUR SYRUP out of reach of children

Store at room temperature

FAQs ABOUT COLDOFER ORANGE FLAVOUR SYRUP
What if I forget to give a dose of COLDOFER ORANGE FLAVOUR SYRUP to my child?
If you forget to give a dose of COLDOFER ORANGE FLAVOUR SYRUP to your child, give it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not give the medicine two times to make up for the forgotten dose.
Can I stop giving COLDOFER ORANGE FLAVOUR SYRUP to my child if the symptoms subside?
Continue giving COLDOFER ORANGE FLAVOUR SYRUP to your child until your child?s doctor tells you to stop, unless your experience child?s any unwanted effects, worsening of the condition or any new symptoms. In such cases, contact your child?s doctor right away.
What precautions do I need to follow while giving COLDOFER ORANGE FLAVOUR SYRUP to my child?
Before giving COLDOFER ORANGE FLAVOUR SYRUP to your child, you must inform child?s doctor about their pre-existing conditions like any kidney, liver, heart or thyroid problems, diabetes, fits or severely raised blood pressure and any other allergies. Consult your child?s doctor if your child experiences anything different.
Can I give other medicines to my child along with COLDOFER ORANGE FLAVOUR SYRUP?
Before giving COLDOFER ORANGE FLAVOUR SYRUP to your child, inform your child?s doctor if your child is taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicines, as these might interact with each other and cause serious side effects.
Can?COLDOFER ORANGE FLAVOUR SYRUP be used in children with liver problems?
COLDOFER ORANGE FLAVOUR SYRUP should be used with caution in children with liver impairment. Child?s doctor may monitor your child?s liver function before and during treatment with this medicine to prevent the risk of any unusual effects. Consult your child?s doctor for advice before administration of COLDOFER ORANGE FLAVOUR SYRUP to your child.
REFERENCES
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Allergic Rhinitis. Pharmacotherapy Handbook. Ninth edition. Page- 813.
2. KD. Tripathi. Adrenergic System and Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page ? 135.
3. Mayuresh Kiran?and Lalit Pawaskar. Study of Safety and Efficacy for the Combination of Chlorpheniramine maleate and Phenylephrine in Infants suffering from Allergic Rhinitis and Associated Symptoms. International Research of Contemporary Medical Research. March 2019. [Accessed on 20th July 2022]?https://www.ijcmr.com/uploads/7/7/4/6/77464738/ijcmr_2406_v1.pdf
4. PubChem Compound Summary for CID 2725, Chlorpheniramine. National Center for Biotechnology Information. June 2022. [Accessed on 20th July 2022]?https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine#section=Mechanism-of-Action
5. Centaur Pharmaceuticals Pvt. Ltd. and Lab Daffodil. Sinarest AF Drops (Phenylephrine + Chlorpheniramine). [Revised in January 2022] [Accessed on 20th July 2022]?https://www.centaurpharma.com/downloads/2022/pediatrics/cold/Sinarest%20AF%20oral%20drops.pdf
6. Centaur Pharmaceuticals Pvt. Ltd. and Lab Daffodil. Sinarest AF Drops/Syrups [Accessed on 20th July 2022]?https://www.centaurpharma.com/downloads/Sinarest-AF-Syr-Drops2018.pdf
7. Zuventus Healthcare Limited. Maxtra Syrup (Phenylephrine + Chlorpheniramine maleate). [Accessed on 20th July 2022]?http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=149
8. GlaxoSmithKline Consumer Healthcare. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 20th July 2022]?https://www.medicines.org.uk/emc/files/pil.3928.pdf
USEFUL DIAGNOSTIC TESTS