Dalacin C Injection 600 mg 1 Ampx4 mL works primarily by binding to the 50s ribosomal subunit of bacteria. This agent disrupts protein synthesis by interfering with the transpeptidation reaction, which thereby inhibits early chain elongation.
Side effects
Major & minor side effects for Dalacin C Injection 600 mg 1 Ampx4 mL

Scaly skin severe

Black or tarry stools severe

Nausea

Chest pain severe

Diarrhea severe

Abdominal pain

Fast heartbeat severe

Muscle or joint pain severe

Increased thirst severe

Uses of Dalacin C Injection 600 mg 1 Ampx4 mL
What is it prescribed for?

Lower Respiratory Tract Infection
This medicine is used in the treatment of infections of the lower respiratory tract such as bronchitis, pneumonia, etc. caused by susceptible staphylococcal, pneumococcal, and streptococcal species as well as anaerobic bacteria.

Skin and Skin Structure Infection
This medicine is used in the treatment of skin and skin structure infections caused by susceptible staphylococcal and streptococcal species as well as anaerobic bacteria.

Intra-abdominal Infections
This medicine is used in the treatment of intra-abdominal infections such as peritonitis, intra-abdominal abscess, etc. caused by susceptible anaerobic bacteria.

Gynecological infections
This medicine is used in the treatment of gynecological infections such as vulvitis, vaginitis, endometritis, etc. caused by susceptible anaerobic bacteria.

Bone and Joint infections
This medicine is used as an adjunctive therapy along with surgical procedures for the treatment of chronic bone and joint infections caused by susceptible bacteria.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed within 1 to 3 hours after an intramuscular administration and rapidly after an intravenous administration.

Duration of Effect
The effect of this medicine lasts for an average duration of 6 to 8 hours.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary. Your doctor may prescribe a safer alternative based on your clinical condition.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Dalacin C Injection 600 mg 1 Ampx4 mL , any other lincosamides, or any other inactive ingredients present along with it.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary. Your doctor may prescribe a safer alternative based on your clinical condition.

General Warnings

Clostridium difficile-associated Diarrhea
Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Skin reactions
Usage of this medicine is known to cause severe skin reactions such as toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and Stevens-Johnson syndrome (SJS), etc. in rare cases, some with fatal outcomes. Report any unusual symptoms to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Gasping syndrome
Some formulations of this medicine may contain benzyl alcohol; these formulations increase the risk of the gasping syndrome in the newborns. Formulations without benzyl alcohol may be preferred for such patients.

Impaired liver function
This medicine should be used with caution in patients with a known history of an impaired liver function due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Impaired kidney function
This medicine should be used with caution in patients with a known history of an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Intravenous Administration
When used intravenously, the infusion rate of the medicine varies based on the prescribed dose.

Dosage

Missed Dose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Gentamicin moderate

Ethinyl Estradiol moderate

Cholera Vaccine severe

Verapamil moderate

Erythromycin moderate

Cyclosporine moderate

Disease interactions

moderate
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, due to the increased risk of worsening of the patient’s condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

moderate
This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

moderate
This medicine should be used with caution in patients with renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

General Instructions

This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

References

wikipedia.org –
Clindamycin [Internet].
Available from: https://en.wikipedia.org/wiki/Clindamycin
[cited 6/7/2020].
2020

uptodate.com –
Clindamycin [Internet].
Available from: https://www.uptodate.com/contents/clindamycin-an-overview#:~:text=Clindamycin%20works%20primarily%20by%20binding,thereby%20inhibits%20early%20chain%20elongation.
[cited 6/7/2020].