INTRODUCTION
DEVAN ER 50MG contain desvenlafaxine which belongs to a group of medicine called SNRIs (serotonin-norepinephrine reuptake inhibitors). It is used to treat depression. This medicine works by increasing the levels of chemical messengers such as serotonin and noradrenaline in the brain that help maintain mental balance.
Always take DEVAN ER 50MG exactly as your doctor has told you. This medicine must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine. This medicine is strictly not recommended for use in children and adolescents. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effects are nausea, vomiting, sweating, dizziness, insomnia, constipation, diarrhoea, loss of appetite, anxiety, decreased sex drive, delayed orgasm, and ejaculation.
USES OF DEVAN ER 50MG

Treat depression

HOW DEVAN ER 50MG WORKS
DEVAN ER 50MG works by increasing the levels of chemical messengers such as serotonin and noradrenaline, natural substances in the brain that help maintain mental balance.
DIRECTIONS FOR USE
Always take DEVAN ER 50MG exactly as your doctor has told you. It must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.
SIDE EFFECTS OF DEVAN ER 50MG

SERIOUS

Serious mental illnesses and suicidal thoughts

Serotonin syndrome or neuroleptic malignant syndrome

Restlessness

Hallucinations

Increase in blood pressure

Loss of coordination or coma

Fast heartbeat

Increased body temperature

Muscle stiffness

New or worsened high blood pressure (hypertension)

Abnormal bleeding or bruising

Glaucoma

Increased cholesterol and triglyceride level in blood

Abnormal dreams and confusion

Seizures (convulsions)

Allergic reactions such as swelling beneath the skin (e.g.throat, face, hands)

COMMON

Nausea, vomiting, headache

Dry mouth

Sweating

Dizziness, insomnia or sleepiness

Constipation, diarrhoea

Loss of appetite

Tiredness, anxiety, tremor

Dilated pupils

Decreased sex drive

Delayed orgasm and ejaculation

Feeling that your surroundings are spinning or moving

HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Dry mouth:
Chew sugar-free gum or suck on sugar-free hard candies. Control your caffeine intake. Do not use mouthwashes. Sip water regularly.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy. ?
Constipation:?
Eat fibre rich foods?such as fresh fruit, vegetables and cereals, and drink plenty of water.?Exercise more regularly.
Diarrhoea:
Drink lot of fluids such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.
Sleepiness:
Get up and move around to feel awake. Take a nap to take the edge off the sleepiness. Give your eyes a break to avoid weakness.
WARNING & PRECAUTIONS

PREGNANCY
DEVAN ER 50MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.
BREASTFEEDING
DEVAN ER 50MG should be used with caution in breast-feeding women. Consult your doctor before taking?this medicine.
DRIVING AND USING MACHINES
Do not drive a car or operate machinery until you know how DEVAN ER 50MG affects you.
ALCOHOL
Consumption of alcohol is not recommended during treatment with DEVAN ER 50MG.
KIDNEY
DEVAN ER 50MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
DEVAN ER 50MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take DEVAN ER 50MG if you are allergic (hypersensitive) to desvenlafaxine or any other ingredients in this medicine.
HEART DISEASE
DEVAN ER 50MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you have
High blood pressure

High cholesterol or high triglycerides

A history of a stroke

Or had depression, suicidal thoughts or behavior

Glaucoma

Or had bleeding problems

Or had seizures or convulsions

Mania or bipolar disorder

Low sodium levels in your blood

INTERACTIONS
Talk to your doctor if you are taking,
Triptans (used to treat migraine headaches)

Tricyclics, lithium, selective serotonin reuptake inhibitor (SSRIs), serotonin norepinephrine reuptake inhibitor (SNRIs), antipsychotic drugs, or other dopamine antagonists, such as metoclopramide (used to treat mood, anxiety, psychotic, or thought disorders)

Silbutramine

Tramadol

St. John?s Wort

MAOIs (including linezolid, an antibiotic)

Tryptophan supplements

Other medicines containing venlafaxine

SYNOPSIS

Drug :?? Desvenlafaxine

Pharmacological Category :??
Antidepressant, Serotonin/Norepinephrine Reuptake Inhibitor
Therapeutic Indication :??
Depression
Dosage Forms :?? Tablet

MORE INFORMATION
Store below 20-25?C and keep out of reach of children.
FAQs ABOUT DEVAN ER 50MG
Will DEVAN ER 50MG affect my sex drive?
This medicine may cause a decrease in sexual desire and ability. It may also cause delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking this medicine.
Can DEVAN ER 50MG cause Constipation?
Yes, this medicine may cause constipation in some individuals. Eat fibre rich foods?such as fresh fruit, vegetables and cereals, and drink plenty of water.?Exercise more regularly.
Is DEVAN ER 50MG good for anxiety?
It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.
REFERENCES
1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page ? 1088-1092.
2. Daniel Z Lieberman and Suena H Massey. Desvenlafaxine in major depressive disorder: an evidence-based review of its place in therapy. US National Library of Medicines, National Institutes of Health. 15 Jun 2010. [Accessed 01 Dec 2020]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899788/
3.?Wyeth pharmaceuticals Inc,2008; U.S. Food & Drug Administration; [Revised on Oct 2011] [Accessed 01 Dec 2020]?https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021992s030lbl.pdf
PRODUCT DETAILS

Net Qty

1 N

Item Weight

17.5 g

Ingredient

DESVENLAFAXINE 50 mg

Hsn Code

30049099

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