DI-HYDEN 100mg Tablet 100s works by decreasing abnormal electrical activity in the brain.
Side effects
Major & minor side effects for DI-HYDEN 100mg Tablet 100s

Decreased coordination

Nervousness

Unsteadiness

Shaking of hands or feet rare

Unusual facial expressions rare

Trouble sleeping

Uncontrolled eye movements

Yellow colored eyes or skin rare

Skin rash rare

Headache rare

Uses of DI-HYDEN 100mg Tablet 100s
What is it prescribed for?

Seizures
This medicine is used for the treatment of tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures (a brain disorder characterized by uncontrolled jerking movements and loss of consciousness). It is also used to control and/or prevent seizures that may occur during or after brain surgeries or severe head injuries.

Concerns

Frequently asked questions

Onset of action
The peak effect of this medicine can be observed in 1.5 to 3 hours after administration.

Duration of Effect
The effect of this medicine lasts for an average duration of 2 to 3 days.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit forming tendency has been reported

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to DI-HYDEN 100mg Tablet 100s or any other inactive ingredients present along with the formulation.

Delavirdine
This medicine is not recommended for use in patients receiving delavirdine, an antiviral medicine used for the treatment of an HIV infection, since it may worsen the patient’s condition.

Heart rhythm disorders
This medicine is not recommended for use in patients suffering from heart rhythm disorders such as sinus bradycardia, sino-atrial block, second or third-degree AV-block, Adams-Stokes syndrome, etc. due to the increased risk of worsening of the patient’s condition.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

General Warnings

Withdrawal symptoms
Abrupt discontinuation of this medicine may increase the risk of severe adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Suicidal thoughts
This medicine may increase the risk of suicidal thoughts upon treatment. Therefore, it should be used with caution, especially in patients suffering from depression or suicidal tendencies. Close monitoring of mood and behavior is necessary for such patients. Appropriate caregiver and patient counseling, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Skin reactions
This medicine should be used with caution since it may cause skin reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis, Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), etc. in some patients. The treatment should be discontinued if any symptoms of a skin rash appear.

Effects on bone
This medicine is known to decrease bone density and may increase the risk of osteoporosis and osteomalacia. Inform the doctor if you have any bone disorder. Close monitoring of Vitamin-D levels and radiological findings is necessary while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Megaloblastic anemia
This medicine should be used with caution in patients suffering from megaloblastic anemia or folate deficiency due to the increased risk of worsening of the patient’s condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or operating machinery
This medicine may cause dizziness, blurred vision, or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.

Blood cell count
This medicine may cause neutropenia, anemia, and aplastic anemia. Frequent monitoring of blood cell count is necessary. Any signs of low blood count should be reported to the doctor. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Voriconazole severe

Warfarin moderate

Ethinyl Estradiol severe

Metaxalone moderate

Disease interactions

severe
This medicine should be used with caution patients with porphyria due to the increased risk of worsening of the patient’s condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

moderate
This medicine should be used with caution in patients suffering from cardiovascular diseases and conduction abnormalities due to the increased risk of worsening of the patient’s condition. Close monitoring of the heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

moderate
This medicine should be used with caution in patients suffering from diabetes mellitus due to the increased risk of elevated blood sugar levels. Close monitoring of blood sugar levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

severe
This medicine should be used with caution in patients suffering from liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

severe
This medicine should be used with caution in patients suffering from kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesired side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

References

medlineplus.gov –
Phenytoin [Internet].
Available from: https://medlineplus.gov/druginfo/meds/a682022.html
[cited 15/7/2020].
2020