DOXOFRONIC Tablet 10?s Allschoolabs -

Description

INTRODUCTION
DOXOFRONIC TABLET contains Doxofylline which belongs to theroup of medicines called Bronchodilators. It is used to treat asthma and chronic obstructive pulmonary disease (COPD). It can also be used to reduce apnea (lack of breathing) and other respiratory diseases associated with bronchospasm (tightening of airways).
Asthma is a long-term respiratory disease in which your airways become inflamed, swollen and narrowed. It also causes excessive mucous secretion in the airways which makes it difficult for the air to pass through, leading to unpleasant symptoms like wheezing, difficulty in breathing, chest pain and/or cough.
COPD is a lung disease characterized by chronic lung inflammation and obstructed air flow within the airways. It causes wheezing, breathing difficulties, cough with mucus production and chest pain.
During treatment with DOXOFRONIC TABLET your doctor will periodically monitor the levels of doxofylline in your blood as a precaution and would adjust the dose accordingly. Limit the consumption of caffeine containing foods and beverages (such as coffee) while taking DOXOFRONIC TABLET.
Before taking DOXOFRONIC TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have hypertension, hyperthyroidism, stomach ulcers or any concomitant infections as a precaution.
DOXOFRONIC TABLET is not recommended for use in patients with severe hypotension or heart problems (such as myocardial infarction). It is also not suitable for use in breastfeeding women.
Inform your doctor before taking DOXOFRONIC TABLET if you are pregnant or planning to become pregnant. The most common side effects of taking DOXOFRONIC TABLET are nausea, vomiting, upper stomach pain, irritability, lack of sleep and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.
USES OF DOXOFRONIC TABLET
It is used to treat:
Bronchial Asthma

Chronic Obstructive Pulmonary Disease (COPD)

Apnea (breathing stops for a brief period)

HOW DOXOFRONIC TABLET WORKS
DOXOFRONIC TABLET is a bronchodilator. It relaxes the smooth muscles of the airways by blocking the release of certain enzymes (phosphodiesterase) in the respiratory tract that triggers narrowing. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier.
DIRECTIONS FOR USE
Take DOXOFRONIC TABLET as advised by your physician. Swallow the medicine with alass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose, duration of therapy and number of doses per day depending upon your age, body weight and disease condition.
Do not stop taking DOXOFRONIC TABLET once your symptoms subside without consulting your doctor.
SIDE EFFECTS OF DOXOFRONIC TABLET

COMMON

Nausea, vomiting

Upper stomach pain

Headache

Irritability

Lack of sleep (insomnia)

Abnormal or rapid heartbeat

Fast breathing

RARE

Hyperglycemia (high blood sugar levels)

Albuminuria (presence of albumin in urine)
Stop taking DOXOFRONIC TABLET and consult your doctor immediately if you experience any of the following side effects:
Cardiac arrhythmias

Fits (tonic-clonic seizures)

HOW TO MANAGE SIDE EFFECTS
Nausea and Vomiting:
Take DOXOFRONIC TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
WARNING & PRECAUTIONS

PREGNANCY
There is no adequate information regarding the use of DOXOFRONIC TABLET in pregnant women. Therefore, it should be used in pregnant women only if considered necessary by the physician.
BREASTFEEDING
DOXOFRONIC TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
DOXOFRONIC TABLET does not affect your ability to drive or operate machines. However, do not drive or handle any heavy tools or machines if your ability is affected by DOXOFRONIC TABLET.
KIDNEY
DOXOFRONIC TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
DOXOFRONIC TABLET should be used with caution in patients with liver diseases. Therefore, consult your doctor before taking it.
ALLERGY
Talk to your doctor before taking DOXOFRONIC TABLET if you are allergic to Doxofylline or to any other similar medicines (such as etophylline, aminophylline).
HEART DISEASE
DOXOFRONIC TABLET is not recommended for use in patients with heart problems (such as heart attack or myocardial infarction). It should be used with caution in patients with congestive heart failure. Therefore, consult your doctor before taking it.
OTHERS
DOXOFRONIC TABLET is not recommended for use if you:
Have severe hypotension (low blood pressure)
Before taking DOXOFRONIC TABLET tell your doctor if you:
Have concomitant infections

Have hypertension (high blood pressure)

Have severe hypoxemia (low oxygen levels in blood)

Have hyperthyroidism

Have chronic cor pulmonale (right side of the heart fails to function properly)

Have peptic ulcer
Use in Pediatrics:
There is no adequate information regarding the use of DOXOFRONIC TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.
Use ineriatrics:
DOXOFRONIC TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
INTERACTIONS
A) Drug-Drug Interactions:
Before taking DOXOFRONIC TABLET, inform your doctor if you are taking any of the following medicines such as:
Other methylxanthines (used to treat respiratory problems) Ex. etophylline, aminophylline

Medicines used to treat bacterial infections (such as erythromycin, troleandomycin, lincomycin, clindamycin)

Allopurinol (a medicine used to treatout)

Cimetidine (a medicine used to treat stomach ulcers)

Influenza vaccine

Propranolol (a medicine used to treat heart problems)

Phenytoin (a medicine used to treat fits)

Sympathomimetic drugs (medicines used to increase heart rate and hypertension) Ex. ephedrine
B) Drug-Food Interactions:
Limit the consumption of foods and beverages rich in caffeine (such as coffee) while taking DOXOFRONIC TABLET.
Overdosage:
If you or anyone else accidentally took more DOXOFRONIC TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS

Drug :?? Doxofylline

Pharmacological Category :?? Methylxanthines

Therapeutic Indication :?? Bronchial Asthma, Chronic Obstructive Pulmonary Disease, Apnea

Dosage Forms :?? Tablet, Syrup, Injection

MORE INFORMATION

Keep DOXOFRONIC TABLET out of reach of children

Store DOXOFRONIC TABLET at room temperature

FAQs ABOUT DOXOFRONIC TABLET
How DOXOFRONIC TABLET works?
DOXOFRONIC TABLET is a bronchodilator. It relaxes the smooth muscles of the airways by blocking the release of certain enzymes (phosphodiesterase) in the respiratory tract that triggers narrowing. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier.
What is the use of DOXOFRONIC TABLET?
DOXOFRONIC TABLET is used to treat asthma and chronic obstructive pulmonary disease (COPD). It can also be used to reduce apnea (lack of breathing) and other respiratory diseases associated with bronchospasm (tightening of airways).
Can I take DOXOFRONIC TABLET daily?
DOXOFRONIC TABLET isenerally prescribed as two/three doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.
Is DOXOFRONIC TABLET effective?
Yes. DOXOFRONIC TABLET effectively controls the symptoms of asthma, COPD ?and other breathing problems, by relaxing the smooth muscles of the airways. As a result, it widens the airways, allows the air to pass through more freely and makes breathing easier
What will happen if I consume a high dose of DOXOFRONIC TABLET than prescribed by my doctor?
Do not consume a higher dose of DOXOFRONIC TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose, is not working for you, consult your doctor for advice.
Is DOXOFRONIC TABLET safe?
DOXOFRONIC TABLET is considered safe at doses prescribed by the physician. However, it may cause few side effects such as stomach pain, headache, nausea, vomiting, irritability, lack of sleep or fast breathing or heart rate in some individuals. Contact your doctor if they bother you.
What should I do if I forgot to take a dose of DOXOFRONIC TABLET?
If you forgot to take a dose of DOXOFRONIC TABLET, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of DOXOFRONIC TABLET to compensate the missed dose.
Will taking a higher dose of DOXOFRONIC TABLET be more effective?
No. Do not take a higher dose of DOXOFRONIC TABLET than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
I?m pregnant. Can I take DOXOFRONIC TABLET?
DOXOFRONIC TABLET should be used in pregnant women only if it is considered necessary by the physician. Your doctor will prescribe you with DOXOFRONIC TABLET after evaluating the risks and benefits of the therapy.
Can DOXOFRONIC TABLET be used in children?
There is no adequate information regarding the use of DOXOFRONIC TABLET in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice before taking it.
Can I stop using DOXOFRONIC TABLET once my symptoms subside?
No. Continue to use DOXOFRONIC TABLET as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.
Can DOXOFRONIC TABLET be used on an asthma attack?
No. DOXOFRONIC TABLET is only used to prevent or manage the symptoms of asthma. If your asthma or breathingets worse suddenly, contact your doctor immediately oro to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler for treating your condition.
How to take DOXOFRONIC TABLET?
Take DOXOFRONIC TABLET as advised by your physician. Swallow the medicine with alass of water. Do not crush or chew the medicine.
What are the side effects of taking DOXOFRONIC TABLET?
The most common side effects of taking DOXOFRONIC TABLET are nausea, vomiting, upper stomach pain, irritability, lack of sleep and fast heartbeat or breathing. Consult your doctor if any of these side effect worsens.
REFERENCES
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of Medical Pharmacology. Page ? 227.
2. Paola Rogliani,?Luigino Calzetta,?Josuel Ora,?Mario Cazzola?&?Mariaabriella Matera. Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis. BMC. Multidisciplinary Respiratory Medicine. August 2019. [Accessed on 15th November 2022]. https://mrmjournal.biomedcentral.com/articles/10.1186/s40248-019-0189-0
3. A.B.C Farmaceutici S.P.A. Doxofylline. [Revised in March 2011] [Accessed on 15th November 2022]. https://www.abcfarmaceutici.it/uploads/news/40_file3_en.pdf
4. Central Drugs Standard Control Organization (CDSCO). Doxofylline MR Tablet 650mg. Doxofylline Tablet (400mg) and Doxofylline tablets & Syrup. [Accessed on 15th November 2022]. https://cdscoonline.gov.in/CDSCO/Drugs
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