GLYCOHALE Respules 7X1ml Allschoolabs -

GLYCOHALE Respules 7X1ml

?Glycopyrrolate 25 mcg

INTRODUCTION:-
GLYCOHALE RESPULES containslycopyrrolate which belongs to theroup of medicines called Anticholinergics. It is used for maintenance treatment of airflow obstruction in patients having chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the lung that causes congested airflow from the lungs. Symptoms of COPD include difficulty in breathing, cough, mucus (sputum) production and wheezing. It is usually caused by long-term exposure to irritatingases or particulate matter, most often from cigarette smoke.
Before usingLYCOHALE RESPULES, inform your physician if you have kidney diseases,laucoma, prostate or bladder problems or problems in passing urine.LYCOHALE RESPULES should be used with caution among pregnant and breastfeeding women only if clearly advised by the doctor.LYCOHALE RESPULES should not be used in children younger than 18 years of age.
The most common side effects of usingLYCOHALE RESPULES are shortness of breath and urinary tract infections. Contact your physician if any of the symptoms worsen.
USES OF LYCOHALE RESPULES:-
Treats chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema
HOW LYCOHALE RESPULES WORKS:-
GLYCOHALE RESPULES works by blocking the action of a chemical messenger (acetylcholine) in the brain. This causes bronchodilation and helps the muscles around the lungs to stay relaxed and decreases COPD symptoms like coughing, chest tightness and shortness of breath.
DIRECTIONS FOR USE:-
UseLYCOHALE RESPULES as advised by your physician. It is for oral inhalational use only. It is administered by nebulization using with nebulizer (with a face mask or mouthpiece) which is connected to an air compressor. Your doctor willuide on how to use the nebulizer. Do not exceed the recommended dose ofLYCOHALE RESPULES. Your doctor will decide the correct dose and duration ofLYCOHALE RESPULES for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OFLYCOHALE RESPULES:-

COMMON

Shortness of breath

Urinary tract infections (strong urge to urinate that doesn?to away, burning feeling when urinating, frequent urination and passing small amounts of urine)
Stop usingLYCOHALE RESPULES and contact your physician immediately if you experience any of the following side effects:
Sudden breathing problems or shortness of breath

Serious allergic reaction (symptoms include rash, hives, swelling of the tongue, lips and face and difficulty breathing or swallowing)

Acute narrow-anglelaucoma (symptoms include eye pain or discomfort, red eyes, blurred vision, seeing halos or bright colors around a light and nausea or vomiting)

Urinary retention (symptoms include difficulty urinating, painful urination, urinating frequently and urination in a weak stream or drips)
HOW TO MANAGE SIDE EFFECTS:-

Nausea:

Use this medicine with or just after meals. Stick to simple meals. Avoid eating rich or spicy food. Ask for your doctor?s advice if nausea doesn?t improve.

Vomiting:

Try and eat light, bland foods and avoid fried, oily or sweet foods. Ask for your doctor?s advice if vomiting doesn?t improve.
WARNING & PRECAUTIONS:-

PREGNANCY

GLYCOHALE RESPULES should be used with caution in pregnant women only if clearly advised by the doctor. Inform your doctor if you become pregnant while usingLYCOHALE RESPULES. Consult your doctor before using.

BREASTFEEDING

GLYCOHALE RESPULES should be used with caution in breastfeeding women only if clearly advised by the doctor as it is not known ifLYCOHALE RESPULES passes through mother?s milk. Consult your doctor before using.

DRIVING AND USING MACHINES

GLYCOHALE RESPULES does not alter your ability to drive or use machines.

KIDNEY

GLYCOHALE RESPULES should be used with caution in patients with kidney disease. Consult your physician before using it.

ALLERGY

Do not useLYCOHALE RESPULES if you are allergic tolycopyrrolate or to any of the other ingredients of this medicine.
OTHERS:-
Before usingLYCOHALE RESPULES, inform your physician if you have:
Glaucoma (increased pressure within the eye)

Prostate or bladder problems

Problems in passing urine
Use in pediatrics:
GLYCOHALE RESPULES is not recommended to use in children and adolescents younger than 18 years of age as the safety and effectiveness ofLYCOHALE RESPULES has not been established in thisroup. Consult your physician before using it for your child.
Use ineriatrics:
No overall difference in safety or effectiveness ofLYCOHALE RESPULES were observed between the elderly and younger patients. Consult your physician before using it.
INTERACTIONSL:-
A. Drug-Drug interactions:
Before usingLYCOHALE RESPULES, inform your physician if you are taking any of the following medicine:
Other anticholinergic drugs such as umeclidinium, tiotropium, ipratropium, aclidinium (used to treat asthma)

Sympathomimetics such as phenylephrine, pseudoephedrine (used in cough or cold)

Corticosteroids such as prednisolone (used to treat inflammation)
Overdosage:
If you or anyone else accidentally use too much ofLYCOHALE RESPULES, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage are nausea, vomiting, dizziness, lightheadedness, blurred vision, increased intraocular pressure (causing pain, vision disturbances or reddening of the eye), obstipation (severe form of constipation) or difficulties in voiding (urination).
SYNOPSIS:-
Drug :??lycopyrrolate
Pharmacological Category :?? Anticholinergics
Therapeutic Indication :?? COPD (Chronic Pulmonary Obstructive Disease)
Dosage Forms :?? Tablet, Injection, Respules, Transpule
MORE INFORMATION:-
KeepLYCOHALE RESPULES out of reach of children

StoreLYCOHALE RESPULES at a temperature, not more than 25?C
FAQs ABOUTLYCOHALE RESPULES:-
Why isLYCOHALE RESPULES prescribed to me?
GLYCOHALE RESPULES is used maintenance treatment of airflow obstruction in patients having chronic obstructive pulmonary disease (COPD), including chronic bronchitis or emphysema. Consult your physician before usingLYCOHALE RESPULES.
How to takeLYCOHALE RESPULES?
TakeLYCOHALE RESPULES as advised by your physician. It is for oral inhalational use only. It is administered by nebulization using with nebulizer (with a face mask or mouthpiece) which is connected to an air compressor. Your doctor willuide on how to use the nebulizer. Do not exceed the recommended dose ofLYCOHALE RESPULES. Your doctor will decide the correct dose and duration ofLYCOHALE RESPULES for you depending upon your age, body weight and disease condition.
What are the common side effects ofLYCOHALE RESPULES?
The most common side effects of usingLYCOHALE RESPULES are shortness of breath and urinary tract infections. Contact your physician for advice if any of the symptoms worsen.
What happens if I use moreLYCOHALE RESPULES?
If you or anyone else accidentally use too much ofLYCOHALE RESPULES, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage are nausea, vomiting, dizziness, lightheadedness, blurred vision, increased intraocular pressure (causing pain, vision disturbances or reddening of the eye), obstipation or difficulties in voiding.
Is it safe to drive after usingLYCOHALE RESPULES?
GLYCOHALE RESPULES has no or negligible influence on the ability to drive and use machines. However, ask for your physician?s advice.
IsLYCOHALE RESPULES a steroid?
GLYCOHALE RESPULES belongs to theroup of medicines called Anticholinergics. It works by blocking the action of a chemical messenger (acetylcholine) in the brain. This helps the muscles around the lungs stay relaxed and decreases COPD symptoms like coughing, chest tightness and shortness of breath.
Can I stop takingLYCOHALE RESPULES on my own if I start to feel better?
Do not stop usingLYCOHALE RESPULES or other medicines to control or treat your COPD unless told to do so by your doctor because your symptoms mightet worse. If you wish to discontinue usingLYCOHALE RESPULES, ask for your doctor?s advice.
REFERENCES:-
1.?Holly E.urgle and Donald K. Blumenthal. Drug Therapy for Dyslipidemias.oodman &ilman?s The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page ? 605-618.
2. Pierachille Santus, Dejan Radovanovic, Andrea Cristiano, Vincenzo Valenti and Maurizio Rizzi. Role of nebulizedlycopyrrolate in the treatment of chronic obstructive pulmonary disease. NIH National Library of Medicine National Centre for Biotechnology Information. Pumed Central. November 2017. [Accessed on 6th July 2022]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695264/
3. Donald P Tashkin, Nicholas Jross. Inhaledlycopyrrolate for the treatment of chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease. NIH National Library of Medicine National Centre for Biotechnology Information. Pumed Central. June 2018 [Accessed on 6th July 2022]?https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003532
4.?Edward Kerwin, James F. Donohue, ThomasGoodin, RobertTosiello, Alistair Wheeler,ary T.Ferguson. Efficacy and safety oflycopyrrolate / eFlow? CS (nebulizedlycopyrrolate) in moderate-to-very-severe COPD: Results from thelycopyrrolate for obstructive lung disease via electronic nebulizer (GOLDEN) 3 and 4 randomized controlled trials. Journal of Respiratory Medicine. Science Direct. November 2017. [Accessed on 6th July 2022]?https://www.sciencedirect.com/science/article/pii/S095461111730210X
5.lycopyrrolate. https://www.ciplamed.com/. [Revised in November 2019] [Accessed on 6th July 2022]?https://www.ciplamed.com/content/glycohale-respule
6. Sunovion Pharmaceuticals Inc. Dailymed. [Revised in December 2020] [Accessed on 6th July 2022]?https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78166def-5e2f-42a6-a1f1-0253e5765632
7.?Drug bank.lycopyrrolate. [Accessed on 6th July 2022]?https://go.drugbank.com/drugs/DB00986
USEFUL DIAGNOSTIC TESTS:-