Ibipolid 2mg Capsule 21?S Allschoolabs -

Description

INTRODUCTION
IBIPOLID 2MG CAPSULE contains Pomalidomide which belongs to the group of medicines called Immunomodulating agents. It is used in adults to treat multiple myeloma (cancer of plasma cells). It is generally used in combination with other anti-cancer agents (such as dexamethasone and/or bortezomib) to achieve better results.
Before taking IBIPOLID 2MG CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have high blood pressure, high blood cholesterol levels, blood clots or hepatitis B infection or have a habit of smoking as a precaution.
IBIPOLID 2MG CAPSULE is not recommended for use in women who are pregnant, think that they might be pregnant or planning to become pregnant. It should be used in breastfeeding women only if considered necessary by the physician.
Both men and women undergoing therapy with IBIPOLID 2MG CAPSULE must use a suitable contraceptive method to avoid pregnancy prior to, during and until 4 weeks after stopping the therapy. Patients taking IBIPOLID 2MG CAPSULE must not donate their blood during treatment and for 7 days after the end of treatment
The most common side effects of taking IBIPOLID 2MG CAPSULE are increased infections, low RBC and platelet count, nausea, vomiting, swelling of body parts, numbness or tingling of body parts, skin rashes, oral sores, taste changes and weight loss. Consult your doctor if any of these side effect troubles you.
USES OF IBIPOLID 2MG CAPSULE

Treats multiple myeloma (cancer of plasma cells) in adults

HOW IBIPOLID 2MG CAPSULE WORKS
IBIPOLID 2MG CAPSULE stimulates the immune system to stop the growth of abnormal plasma cells (a type of white blood cells) in the blood. This helps in destroying the cancer cells in the blood and prevents it from developing further. It also reduces blood supply to the cancer cells, which helps in preventing further spread of cancer cells in the body.
DIRECTIONS FOR USE
Take IBIPOLID 2MG CAPSULE as advised by your doctor. Swallow the medicines with a glass of water. Do not crush or chew the medicine. It can be taken with or without food.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking IBIPOLID 2MG CAPSULE unless your doctor tells you to stop.
SIDE EFFECTS OF IBIPOLID 2MG CAPSULE

COMMON

Shortness of breath

Infections of lung or respiratory tract (bronchitis, sinusitis, pneumonia)

Anaemia (low RBC in blood causing tiredness and weakness)

Low blood sodium, potassium, magnesium and phosphate levels

High blood calcium levels?

Elevated blood sugar levels

Nausea, vomiting, constipation, diarrhoea, loss of appetite, stomach pain

Lack of energy, muscle weakness

Difficulty in sleeping

Dizziness, tremor, spinning sensation

Numbness, tingling or burning sensation on the body

Swelling of the arms and leg or body

Skin rash, itching, shingles

High blood pressure

High uric acid levels in blood

Changes in taste, mouth ulcers, dry mouth

Feeling confused, depression

Urinary tract infections

Weight loss

UNCOMMON

Tumour lysis syndrome (toxin accumulation in blood due to breakdown of cancer cells)

Decreased thyroid functions

RARE
Stop taking IBIPOLID 2MG CAPSULE and contact your physician immediately if you experience any of the following side effects:
Signs of infections (such as fever, chills, sore throat, cough, mouth ulcers or any other signs of infection)

Increased bleeding or bruising, nasal bleeds, bleeding in the gut

Signs of sepsis (such as fever, chills, low urine output, nausea and vomiting, confusion, rapid breathing)

Severe persistent bloody diarrhea

Signs of blood clot (such as chest pain, shortness of breath, leg pain and swelling, heart failure)

Signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)

Skin cancer, changes in skin colour

Signs of liver damage (such as yellowish discolouration of the skin and eyes, dark, brown-coloured urine, right-sided abdominal pain, fever, nausea and vomiting)

Signs of severe allergic skin reactions (such as skin rash on the face or whole body, redness, high fever, flu-like symptoms with enlarged lymph nodes)

Signs of posterior leukoencephalopathy syndrome (a nerve disorder causing bnormal vision from blurriness to vision loss, problems in walking and speaking, loss of balance, weak arms or legs, memory loss, confusion, fits, headache, numbness of body parts)

HOW TO MANAGE SIDE EFFECTS
Skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Nausea and Vomiting:
Stick to simple meals. Avoid eating oil rich or spicy foods. If your nausea worsens, consult your doctor for advice.
Mouth ulcers:
Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS

PREGNANCY
IBIPOLID 2MG CAPSULE may harm the unborn baby. Therefore, it should not be used in pregnant women and in women who are planning to become pregnant or think that they might be pregnant. Women of childbearing potential must use a suitable contraceptive method to avoid pregnancy prior to the therapy, during the therapy and until 4 weeks after stopping therapy with IBIPOLID 2MG CAPSULE. If you accidentally became pregnant while undergoing therapy with IBIPOLID 2MG CAPSULE, stop taking this medicine and inform your doctor immediately.
BREASTFEEDING
It is not known whether IBIPOLID 2MG CAPSULE passes through breast milk or not. Therefore, it should be used in breastfeeding women only if considered necessary by the physician.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy, tired or faint after taking IBIPOLID 2MG CAPSULE.
KIDNEY
IBIPOLID 2MG CAPSULE should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it
LIVER
IBIPOLID 2MG CAPSULE should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take IBIPOLID 2MG CAPSULE if you are allergic to pomalidomide, lenalidomide or thalidomide.
HEART DISEASE
IBIPOLID 2MG CAPSULE should be used with caution in patients with heart failure or a recent heart attack. Therefore, consult your doctor before taking it.
OTHERS
Before taking IBIPOLID 2MG CAPSULE, inform your doctor if you:
Have ever had blood clots in the past

Have a habit of smoking

Have high blood cholesterol levels

Have high blood pressure

Have breathing difficulties

Have excessive tumours in your body (including tumours of bone marrow)

Have or ever had nerve damage or nerve pain

Have or ever had hepatitis B infection
Use in paediatrics:
IBIPOLID 2MG CAPSULE is not suitable for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use in geriatrics:
IBIPOLID 2MG CAPSULE should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking IBIPOLID 2MG CAPSULE, inform your doctor if you are taking any of the following medicines such as:
Ketoconazole (used to treat fungal infections)

Ciprofloxacin, enoxacin (medicines used for bacterial infections)

Fluvoxamine (used to treat depression)
Overdosage:
If you or anyone else accidentally took more IBIPOLID 2MG CAPSULE, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS

Drug :?? Pomalidomide

Pharmacological Category :?? Immunomodulating agents

Therapeutic Indication :?? Multiple myeloma

Dosage Forms :?? Capsule

MORE INFORMATION

Keep IBIPOLID 2MG CAPSULE out of the sight and reach of children

Store IBIPOLID 2MG CAPSULE at room temperature

FAQs ABOUT IBIPOLID 2MG CAPSULE
What IBIPOLID 2MG CAPSULE is used for?
IBIPOLID 2MG CAPSULE is used in adults to treat multiple myeloma (cancer of plasma cells). It is generally used in combination with other anti-cancer agents (such as dexamethasone and/or bortezomib) to achieve better results.
How IBIPOLID 2MG CAPSULE works on my body?
IBIPOLID 2MG CAPSULE stimulates the immune system to stop the growth of abnormal plasma cells (a type of white blood cells) in the blood. This helps in destroying the cancer cells in the blood and prevents it from developing further. It also reduces blood supply to the cancer cells, which helps in preventing further spread of cancer cells in the body.
Can IBIPOLID 2MG CAPSULE cure cancer?
Multiple myeloma generally cannot be cured. However, treatment with IBIPOLID 2MG CAPSULE can reduce the signs and symptoms of the disease or make them disappear for a short period. For more information, consult your doctor for advice.
Can the use of IBIPOLID 2MG CAPSULE cause weight loss?
Weight loss is one of the common side effects of taking IBIPOLID 2MG CAPSULE. If it bothers you, consult your doctor for advice.
Can the use of IBIPOLID 2MG CAPSULE cause mouth ulcers?
Mouth ulcers are one of the common side effects of taking IBIPOLID 2MG CAPSULE. Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve
Can IBIPOLID 2MG CAPSULE be used in children?
IBIPOLID 2MG CAPSULE should not be used in children aged below 18 years. Therefore, consult your doctor before taking it.
Is IBIPOLID 2MG CAPSULE a chemo drug?
Yes. IBIPOLID 2MG CAPSULE contains a medicine called pomalidomide which is an immunomodulating agent with anti-cancer properties. It stimulates the immune system to stop the growth of abnormal plasma cells (a type of white blood cells) in the blood.
What precautions must be followed while taking IBIPOLID 2MG CAPSULE?
Before taking IBIPOLID 2MG CAPSULE inform your doctor if you have any liver, kidney or heart problems. Inform your doctor before taking IBIPOLID 2MG CAPSULE if you are a pregnant or a breastfeeding woman. Men and women taking IBIPOLID 2MG CAPSULE must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with IBIPOLID 2MG CAPSULE.
What happens if I stop taking IBIPOLID 2MG CAPSULE?
No. Do not stop taking IBIPOLID 2MG CAPSULE without consulting your doctor as it may make your symptoms reappear. Therefore, take IBIPOLID 2MG CAPSULE as advised by your doctor for the stipulated duration.
Can IBIPOLID 2MG CAPSULE be used during pregnancy?
IBIPOLID 2MG CAPSULE is generally not recommended for use in pregnant women. If you accidentally became pregnant while taking IBIPOLID 2MG CAPSULE, inform your doctor immediately.
Can the use of IBIPOLID 2MG CAPSULE make me feel tired?
Yes. IBIPOLID 2MG CAPSULE may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anaemic. Consult your doctor if you experience tiredness after taking IBIPOLID 2MG CAPSULE. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while taking this medicine.
Can I drive a car after taking IBIPOLID 2MG CAPSULE?
IBIPOLID 2MG CAPSULE may make you feel tired or dizzy. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by IBIPOLID 2MG CAPSULE.
How to take IBIPOLID 2MG CAPSULE?
Take IBIPOLID 2MG CAPSULE as advised by your doctor. Swallow the medicines with a glass of water. Do not crush or chew the medicine. It can be taken with or without food.
How to control nausea caused due to IBIPOLID 2MG CAPSULE?
Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with IBIPOLID 2MG CAPSULE. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-treat nausea.
What are the side effects of taking IBIPOLID 2MG CAPSULE?
The most common side effects of taking IBIPOLID 2MG CAPSULE are increased infections, low RBC and platelet count, nausea, vomiting, swelling of body parts, numbness or tingling of body parts, skin rashes, oral sores, taste changes and weight loss. Consult your doctor if any of these side effect troubles you.
Who should avoid taking IBIPOLID 2MG CAPSULE?
IBIPOLID 2MG CAPSULE is not recommended for use if you are allergic to pomalidomide. It is also not recommended for use in pregnant or breastfeeding women and in children (aged below 18 years).
Is IBIPOLID 2MG CAPSULE safe to use in kidney disease?
IBIPOLID 2MG CAPSULE should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.
Can the use of IBIPOLID 2MG CAPSULE affect the liver?
Yes. IBIPOLID 2MG CAPSULE may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
REFERENCES
1. Ashkan Emadi, Judith E. Karp.? Multiple myeloma as a paradigm for multi-targeted intervention. Cancer pharmacology an illustrated manual of anticancer drugs. First edition. 2020. Page -205.
2. A A Chanan-Khan, A Swaika, A Paulus, S K Kumar, J R Mikhael, S V Rajkumar, A Dispenzieri, and M Q Lacy. Pomalidomide: the new immunomodulatory agent for the treatment of multiple myeloma. National Institute of Health. NLM. National Center for Biotechnology Information. Pubmed.gov. September 2013. [Accessed on 3rd December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789204/
3. Celgene Distribution B.V. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 3rd December 2022] https://www.medicines.org.uk/emc/files/pil.3465.pdf
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