INFA HEP Injection 5ml Allschoolabs -

Description

INTRODUCTION
INFA HEP INJECTIONcontains Heparin which belongs to theroup of medicines called Anticoagulants. It is used to treat blood clots in leg veins (deep vein thrombosis), blood clots in the lung (pulmonary embolism), chest pains resulting from disease of the heart arteries (unstable angina pectoris), severe blockages affecting arteries in the legs (acute peripheral arterial occlusion).
INFA HEP INJECTION is also used during heart, lung operations, during kidney dialysis and prevention of blood clots in the heart following a heart attack (mural thrombosis). A blood clot or thrombus is ael-like collection of blood that form in arteries or veins when blood changes from liquid to partially solid form.
INFA HEP INJECTION is not recommended for use if you have liver disease, serious bleeding problems, haemophilia, bruise easily, high blood pressure, tuberculosis, major trauma, have had severe skin problems resulting from previous heparin treatment, surgery of the brain, spine or eye, a lumbar puncture or receiving anesthetic, had an operation, thrombocytopenia, bleeding into the brain, drink a lot of alcohol.
Before receiving INFA HEP INJECTIONinform your doctor if you have kidney disease, diabetes, a condition that makes you bleed easily, or suffer from excess acid or high levels of potassium in your blood. Do not consume alcohol, tobacco, or smoke during this treatment.
INFA HEP INJECTION should be used with caution in pregnant and breastfeeding women. INFA HEP INJECTION is not recommended for use in premature and newborn babies (up to 4 weeks old). Ask for your doctor?s advice.
INFA HEP INJECTION should be used with caution in elderly patients above 60 years of age. The most common side effects of receiving INFA HEP INJECTION are red lumps or red, itchy patches like eczema at injection site. Consult your doctor if symptoms do not show improvement.
USES OF INFA HEP INJECTION
To treat,
Deep vein thrombosis

Pulmonary embolism

Acute peripheral arterial occlusion

Unstable angina pectoris

Prevent clots during heart, lung operations, kidney dialysis

Mural thrombosis

HOW INFA HEP INJECTION WORKS
INFA HEP INJECTION binds to the antithrombin (an enzyme present in the clotting system) which in turn inhibits several clotting factors such as factor Xa, factor IIa. This inactivation of thrombin prevents the formation of clots and prolongs the clotting time of blood.
DIRECTIONS FOR USE
INFA HEP INJECTION will beiven to you only by a doctor or a nurse into a vein as an intravenous infusion. It should not beiven into a muscle. Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.
SIDE EFFECTS OF INFA HEP INJECTION

COMMON

Red lumps or red, itchy patches like eczema at the injection site

RARE

Raised levels of potassium in the blood, particularly in patients with kidney failure or diabetes (feel tired and weak)

Irritation or sloughing of skin at the injection site
Stop receiving INFA HEP INJECTION and contact your doctor immediately if you experience any of the following side effects:
Severe allergic reactions (itchy skin rash, eye irritation, runny nose, wheezing, rapid breathing, blue tinge to the lips, fever, chills, swelling of the eyes and lips, and shock)

Thrombocytopenia may result in the formation of dangerous blood clots causing chest pains, shortness of breath, coughing, dizziness or loss of consciousness

Signs of developing paralysis (after having an epidural or spinal anesthetic, tingling, weakness or numbness in legs or lower body, back pain, incontinence of urine or back passage)

Unusual bruising or purple spots on skin, unusual bleeding fromums, nose, urine, stool, or injury

HOW TO MANAGE SIDE EFFECTS
Itchy skin:
Hot water makes your skin irritated, so avoid taking hot showers. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. To soothe and hydrate irritated skin, apply moisturizers. Contact your doctor if the itching worsens.
WARNING & PRECAUTIONS

PREGNANCY
INFA HEP INJECTION should be used with caution in pregnant women. Inform your doctor or nurse know prior to receiving INFA HEP INJECTION if you are pregnant, wish to become pregnant or have a history of, or have a known risk of miscarriage. If INFA HEP INJECTION isiven, bleeding may be a problem during pregnancy or after delivery. Your bones mayet thinner if you receive INFA HEP INJECTION for a long-time during pregnancy. If you are pregnant and areoing to have an epidural anesthetic, you should stop having the medicine. Consult your doctor before receiving it.
BREASTFEEDING
INFA HEP INJECTION should be used with caution in breastfeeding women as it will beiven to you after evaluating the risk and benefit ratio. Consult your doctor before receiving it.
DRIVING AND USING MACHINES
INFA HEP INJECTION does not affect your ability to drive or use machines.
ALCOHOL
Do not consume alcohol while receiving INFA HEP INJECTION.
KIDNEY
INFA HEP INJECTION should be used with caution patients having kidney disease, dose will be adjusted by your doctor. Consult your doctor before receiving it.
LIVER
INFA HEP INJECTIONis not recommended for use in patients who suffer from severe liver problems which can lead to bleeding into the esophagus. INFA HEP INJECTION should be used with caution in mild to moderate liver disease, dose will be adjusted by your doctor. Consult with your doctor before receiving INFA HEP INJECTION.
ALLERGY
Do not receive INFA HEP INJECTION if you are allergic to Heparin or any other ingredients of this medicine.
OTHERS
INFA HEP INJECTION is not recommended for use if you:
Drink large amounts of alcohol

Have high blood pressure

Are bleeding from anywhere in the body (apart from your normal periods)

Have hemophilia (aenetic disorder) or any other bleeding problem

Have or have ever had thrombocytopenia (prevents blood from clotting properly)

Bruise easily or have lots of purple spots that look like bruises (purpura)

Are suffering from tuberculosis (TB)

Have had severe skin problems resulting from previous treatment with heparin

Are about to have surgery of the spine or eye, brain, or a lumbar puncture

Have recently had an operation

Have bleeding into the brain
Before receiving INFA HEP INJECTION, inform your doctor if you:
Are having an epidural or spinal anesthetic

Have any condition which makes you likely to bleed more easily (stomach ulcer, hiatus hernia, inflammation of the heart, problems in the back of your eye, piles, a stroke, cancer or threatened miscarriage)

Suffer from diabetes

Suffer from excess acid or high levels of potassium in your blood

Smoke
Use in pediatrics:
INFA HEP INJECTION is not recommended for use in premature and newborn babies (up to 4 weeks old). Consult with your child?s doctor.
Use ineriatrics:
INFA HEP INJECTIONshould be used with caution in elderly patients above 60 years of age. Dose will be adjusted by your doctor. Consult your doctor before receiving it.
INTERACTIONS
A. Drug ? Drug interactions:
Before receiving INFA HEP INJECTION, inform your doctor if you are taking any of the following medicine:
Medicines used to treat pain and inflammation (Ex. diclofenac (especially intravenous), ibuprofen, aspirin)

Medicines used to treat shock (Ex. dextran solutions)

Medicines which may interfere with clotting of the blood (Ex. dipyridamole, epoprostenol, clopidogrel or streptokinase)

Medicines used to treat infections (Ex. cephalosporins,entamicin, amikacin, neomycin or tobramycin)

Medicines used to treat high blood pressure or heart problems (Ex. captopril enalapril, lisinopril, ramipril, losartan or valsartan, aliskiren)

Medicines that may increase the potassium level in blood (Ex. amiloride, triamterene, eplerenone or spironolactone)

Glyceryl trinitrateiven into a vein (used for coronary heart disease)

Medicines used to treatout (Ex. probenecid)
Overdosage:
INFA HEP INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms like severe bleeding.
SYNOPSIS

Drug :?? Heparin

Pharmacological Category :?? Anticoagulant

Therapeutic Indication :?? Blood clots

Dosage Forms :??el, Injection, Solution, Topical solution

MORE INFORMATION

Keep INFA HEP INJECTION out of reach of children

Store INFA HEP INJECTION at room temperature below 25?C

FAQs ABOUT INFA HEP INJECTION
Can INFA HEP INJECTION be received by children?
INFA HEP INJECTION is not recommended for use in premature and newborn babies (up to 4 weeks old). Dose will be adjusted by your doctor depending on your age, body weight and disease condition. Consult your doctor before receiving
Can INFA HEP INJECTION be received by pregnant women?
INFA HEP INJECTION should be used with caution in pregnant women. Inform your doctor or nurse know prior to receiving INFA HEP INJECTION if you are pregnant, wish to become pregnant or have a history of, or known risk to miscarriage. If INFA HEP INJECTION isiven, bleeding may be a problem during pregnancy or after delivery. Your bones mayet thinner if you receive INFA HEP INJECTION for a long-time during pregnancy. If you are pregnant and areoing to have an epidural anesthetic, you should stop having the medicine. Consult your doctor before receiving it.
Can I smoke while receiving INFA HEP INJECTION?
Avoid smoking while receiving INFA HEP INJECTION. Tobacco smoke can also interfere with the working of INFA HEP INJECTION. Ask for your doctor?s advice and inform your doctor if you smoke.
Can I Keep receiving INFA HEP INJECTION if I have a planned surgery?
You must remind your doctor that you are having INFA HEP INJECTION before you receive any anesthetic. After you have the anesthetic your doctor or nurse might make regular checks to make sure you are notetting any major bleeding or bruising around your spine which may cause paralysis that could be permanent. After you have the anesthetic, your doctor will tell you when you can take INFA HEP INJECTION again.
Do I need to undergo any diagnostic tests while receiving INFA HEP INJECTION?
The presence of INFA HEP INJECTION in the blood can affect the results of some blood tests such as thyroid tests and the levels of calcium or some antibiotics such asentamicin in the blood. Your doctor might ask you to take several diagnostic tests.
Will I beiven a test dose of INFA HEP INJECTION?
If you suffer from allergies or have previously had an allergic reaction to heparin, a small test dose of INFA HEP INJECTION may beiven first to make sure that you are not allergic to it.
REFERENCES
1. KD Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of medical pharmacology. Eighth Edition. 2019. Page ?663-664
2. Mandana Izadpanah, Hossein Khalili, Mostafa Mohammadi. Comparing safety of heparin as continuous intravenous infusion and multiple subcutaneous injections. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed.gov. December 2015. [Accessed on 10th August 2022] https://pubmed.ncbi.nlm.nih.gov/26689885/
3. Eziafa, Oduah, Robert J. Linhardt, and Susan T. Sharfstein. Heparin: Past, Present, and Future. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubmed Central. September 2016. [Accessed on 10th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039491/
4. CP Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2018] [Accessed on 10th August 2022] https://www.medicines.org.uk/emc/files/pil.1678.pdf
5. CP Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2018] [Accessed on 10th August 2022] https://www.medicines.org.uk/emc/files/pil.1680.pdf
6. Fresenius Kabi. U.S. Food & Drug Administration. [Revised in August 2017] [Accessed on 10th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017029s140lbl.pdf
7. Pfizer Laboratories Div Pfizer Inc. Heparin Sodium. Dailymed. [Revised in May 2020]. [Accessed on 10th August 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=56dc3074-f1c5-45a3-b923-f1d14858e06d
8. Troikaa Pharmaceuticals. Cathflush (Heparin Sodium). [Accessed on 10th August 2022] https://www.troikaa.com/wp-content/uploads/2021/10/Common-Products-List-Novogen-Excluded.pdf
9. Drug bank. Heparin. [Accessed on 10th August 2022] https://go.drugbank.com/drugs/DB01109
USEFUL DIAGNOSTIC TESTS