INTRODUCTION
KETZI CREAM contains Ketoconazole which belongs to the group of medicines called Antifungals. It is used in adults to treat fungal and yeast infections which may appear on the skin of the hands, feet, genital area, trunk, groin, scalp, face, chest or back.
KETZI CREAM is not recommended for eye infections. Before applying KETZI CREAM, inform your doctor if you are using a cream, ointment or lotion that contains a steroid.
KETZI CREAM can be used if you are pregnant or breast-feeding, however, consult your doctor for advice. KETZI CREAM is not recommended for use in children and adolescents (under 18 years of age).
The most common side effects of applying KETZI CREAM are burning sensation, skin redness, or itching. If any of the symptoms worsen, contact your doctor.
USES OF KETZI CREAM
Treats the fungal or yeast infections of skin appearing on:
Trunk, chest, back
Hands, feet
Scalp, face
Groin, genitals
HOW KETZI CREAM WORKS
KETZI CREAM reduces fungal infection by inhibiting the growth of the fungus by weakening the structure and function of the fungal cell membrane.
DIRECTIONS FOR USE
Apply KETZI CREAM as advised by your physician. It is for external use only. Wash the infected area and dry it well. ?Apply it to the affected and immediate surrounding area with clean fingers. Unless the affected skin is on your hands, wash your hands with soap and water after using KETZI CREAM in order to stop you from spreading the infection to other parts of your body or to other people.
Keep using KETZI CREAM until a few days after all symptoms have completely disappeared. This is to prevent your symptoms from recurring.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Usually, you will see improvement after 4 weeks but if you don?t, talk to your doctor.
SIDE EFFECTS OF KETZI CREAM
COMMON
Burning sensation
Skin redness or itching
UNCOMMON
Hypersensitivity
Raised blisters or inflammation of the skin
Shedding of the skin
Problems where the medicine is applied (bleeding, discomfort, dryness, inflammation, tingling)
Skin irritation like rash
Sticky skin
RARE
Stop applying KETZI CREAM and contact your doctor immediately if you experience any of the following side effects:
Severe irritation or reddening of the skin where the medicine has been applied, or other signs of allergy during initial treatment days
Peeling or blistering of the skin
HOW TO MANAGE SIDE EFFECTS
Rash:
Applying a cold compress, damp cloth, or cool showers can bring immediate relief to swelling and reduce itching. Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash persists.
WARNING & PRECAUTIONS
PREGNANCY
KETZI CREAM can be used if you are pregnant, however, consult your doctor for advice.
BREASTFEEDING
KETZI CREAM can be used if you are breast-feeding, however, consult your doctor for advice.
DRIVING AND USING MACHINES
KETZI CREAM is unlikely to affect your ability to drive or to use machinery.
ALLERGY
Do not apply KETZI CREAM if you are allergic to Ketoconazole or any of the other ingredients of this medicine.
OTHERS
KETZI CREAM is not recommended for eye infections. Consult your doctor for advice.
Use in pediatrics:
KETZI CREAM is not recommended for use in children and adolescents (under 18 years of age). Consult your child?s doctor for advice.
INTERACTIONS
A. Drug ? Drug interactions:
Before applying KETZI CREAM, inform your doctor if you are using the following medicines:
Medicines used to treat inflammatory conditions (Ex. betamethasone, hydrocortisone)
Overdosage:
If you or anyone else accidentally apply too much of KETZI CREAM, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include burning sensation, redness or swelling.
SYNOPSIS
Drug :?? Ketoconazole
Pharmacological Category :?? Azole antifungal
Therapeutic Indication :?? Fungal infections
Dosage Forms :?? Tablet, Solution, Scalp Solution, Cream, Gel, Lotion, Ointment, Shampoo, Soap, Body Wash, Bar, Eye Drops, Dusting Powder, Scrub?
MORE INFORMATION
Keep KETZI CREAM out of reach of children
Do not store above 25?C
FAQs ABOUT KETZI CREAM
How often should I apply KETZI CREAM?
Your doctor will decide the correct dose and duration of KETZI CREAM for you depending upon your age, body weight and disease condition. Depending on the infection type, treatment may last 2 to 6 weeks. Do not apply it for more duration than advised by your doctor.
What if I swallow KETZI CREAM?
Accidental swallowing of small quantities of KETZI CREAM is usually harmless but, consult your doctor immediately if you or anyone else swallow it. Take the medicine with you for the doctor to know what you have ingested.
How do I apply KETZI CREAM?
Apply KETZI CREAM as directed by your physician. Wash the infected area and dry it properly. Keep a towel and a flannel for your personal use to prevent infecting anyone else. Apply the medicine gently into the affected area and surrounding skin with clean fingers. Clothing which touches the infected areas should be washed and changed frequently. Consult your doctor if you have any doubts regarding its use.
What if I forget to apply KETZI CREAM?
If you forget to apply KETZI CREAM, use as per the directions next time you apply it. Do not use the medicine two times to make up for the missed dose.
Can I stop applying KETZI CREAM?
Do not stop applying KETZI CREAM without asking your doctor. You will usually see signs of improvement after 4 weeks. If not, talk to your doctor. Continue using the medicine until a few days after all symptoms have completely disappeared. Even after your skin is completely cured, you sometimes have to apply the medicine once weekly or once per 2 weeks to prevent your symptoms from coming back.
Can I use other medicines with KETZI CREAM for my skin condition?
Before using KETZI CREAM, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine. If you have been regularly using a lotion or cream, containing a steroid (Ex. betamethasone or hydrocortisone) for your skin condition, you should wait for two weeks before starting treatment with KETZI CREAM. This will stop your condition flaring up while KETZI CREAM starts to work. If you have any queries about stopping your steroid lotion or cream, consult your doctor.
REFERENCES
1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page ? 791, 792.
2. Hadeer Sinawe, Damian Casadesus. Ketoconazole. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed 18th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK559221/
3. Choi FD, Juhasz MLW, Atanaskova Mesinkovska N. Topical ketoconazole: a systematic review of current dermatological applications and future developments. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October 1987. [Accessed on 18th October 2022] https://pubmed.ncbi.nlm.nih.gov/30668185/
4. Janssen Pharmaceutica NV. Health Products Regulatory Authority (HPRA). [Revised in July 2022] [Accessed on 18th October 2022] https://www.hpra.ie/img/uploaded/swedocuments/4bf3b755-f85e-41e5-916a-b7c9a7fc10d6.pdf
5. Janssen Pharmaceutica NV. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed 18th October 2022] https://www.medicines.org.uk/emc/files/pil.970.pdf
6. Palsons Derma. Novale scalp lotion (Ketoconazole 2%). [Accessed on 18th October 2022] https://www.palsonsderma.com/novale-scalp-lotion
7. Praise Pharma. Esava ointment. (Ketoconazole 2%). [Accessed on 18th October 2022] http://www.praisepharma.com/products/anti-fungal_esava-ointment.html
USEFUL DIAGNOSTIC TESTS
Microscopic examination of skin
Country Of Origin
India
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