Largactil tablet 50 mg 50?s works by binding to the receptors and inhibits the release of the chemical substances that cause psychotic symptoms.
Side effects
Major & minor side effects for Largactil tablet 50 mg 50?s

Uncontrolled body movements

Restlessness

Drowsiness

Dry mouth

Blurred vision

Skin rash

Hypoglycemia

Difficulty in breathing

Muscle stiffness

Uses of Largactil tablet 50 mg 50?s
What is it prescribed for?

Schizophrenia
Largactil tablet 50 mg 50?s is used in the treatment of Schizophrenia which is a nervous system disorder characterized by delusions, hallucinations.

Nausea and vomiting
Largactil tablet 50 mg 50?s is used to control nausea and vomiting.

Preoperative sedation
Largactil tablet 50 mg 50?s is used to reduce the anxiety before surgery.

Intractable Hiccups
Largactil tablet 50 mg 50?s is used to control hiccups.

Porphyria
Largactil tablet 50 mg 50?s is used to control symptoms of Porphyria.

Tetanus
Largactil tablet 50 mg 50?s is used as an adjunct in the treatment of tetanus to relieve muscle spasm.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed in 30 to 60 minutes.

Duration of Effect
The effect of this medicine lasts for an average duration of 4 to 6 hours.

Safe with Alchohol?
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving and operating machinery.

Is it habit forming?
No habit forming tendency has been reported

Usage in pregnancy?
This medicine is not recommended for use in pregnant women.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women.

When not to use?

Allergy
Not recommended in patients with known allergy to Largactil tablet 50 mg 50?s or phenothiazines.

Severe central nervous system depression
Not recommended in patients with central nervous system depression disorders.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women.

Breast-feeding
This medicine is not recommended for use in breastfeeding women.

General Warnings

Neuroleptic Malignant Syndrome
Largactil tablet 50 mg 50?s should be discontinued immediately if the patient develops Neuroleptic Malignant Syndrome characterized by an increase in the body temperature, muscle rigidity, altered consciousness.

Tardive dyskinesia
Largactil tablet 50 mg 50?s may cause involuntary movements of tongue, lips, and face. Inform the doctor if you have these symptoms. The dose should be reduced or the medicine discontinued if the symptoms worsen.

Diabetes and Dyslipidemia
Largactil tablet 50 mg 50?s may increase the blood glucose levels in the body. Assess these parameters before initiation of the treatment. Also, regular monitoring of blood glucose and body weight is necessary.

Blood cells count
Largactil tablet 50 mg 50?s may reduce the blood cell count, especially WBC (neutrophils). Any symptoms of fever, weakness during the treatment should be reported to the doctor. The dose should be reduced or the medicine discontinued if the symptoms worsen.

Pediatric use
The safety and efficacy of Largactil tablet 50 mg 50?s is not established in the children less than 6 months of age.

Discontinuation syndrome
Do not stop taking this medicine abruptly as it may cause withdrawal symptoms like nausea, headache, diarrhea, dizziness, and irritability. The dose should be reduced gradually based on the patient’s response under the doctor’s supervision.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Antidiabetic medicines moderate

Opioids severe

Antihypertensives moderate

Levodopa moderate

Disease interactions

severe
This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.

General Instructions

Take Largactil tablet 50 mg 50?s as instructed by the doctor. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor as it may cause withdrawal symptoms.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

References

practo.com –
Chlorpromazine [Internet].
Available from: https://www.practo.com/medicine-info/chlorpromazine-383-api
[cited 3 october 2019].
8 Jan 2018

dailymed.nlm.nih.gov –
Chlorpromazine [Internet].
Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b028fb3d-2939-4197-b31c-ac327f9593ec
[cited 3 october 2019].
August 26, 2019

drugbank.ca –
Chlorpromazine [Internet].
Available from: https://www.drugbank.ca/drugs/DB00477
[cited 3 october 2019].
October 02, 2019