LEVOSALVAC DUO Respules 2.5ml Allschoolabs -

Description

INTRODUCTION
LEVOSALVAC DUO RESPULES is a combination of Ipratropium and Levosalbutamol which belongs to theroup of medicines called Bronchodilator agents and Adrenergic beta-agonists, respectively. LEVOSALVAC DUO RESPULES is used to treat bronchospasm (tightened airway muscles) associated with chronic obstructive pulmonary disease (inflammatory lung disease) in patients who require more than one bronchodilator (medication) to help them in easy of breathing.
LEVOSALVAC DUO RESPULES is not recommended for use in patients allergic to ipratropium, levosalbutamol, and/or atropine.
Before using LEVOSALVAC DUO RESPULES, inform your doctor if you have high blood pressure, seizures, diabetes, narrow anglelaucoma (increased eye pressure), lung problems (such as asthma), heart problems (such as coronary insufficiency, cardiac arrhythmias), kidney problems (such as renal impairment), and/or liver problems (such as hepatic impairment).
LEVOSALVAC DUO RESPULES should be used with caution during pregnancy and in women planning for pregnancy. It is also used with caution in breastfeeding women only if necessary.
LEVOSALVAC DUO RESPULES is not recommended for use in children (aged less than 6 years). It should be used with caution in children and adolescents (aged 6 to 18 years). Consult your doctor before administering LEVOSALVAC DUO RESPULES.
The most common side effects of using LEVOSALVAC DUO RESPULES are headache, dizziness, nervousness, cough, sore throat, local irritation, dry mouth, nausea, and/or diarrhoea. Consult your doctor if any of these symptoms worsens.
USES OF LEVOSALVAC DUO RESPULES

Treats bronchospasm associated with chronic obstructive pulmonary disease (inflammatory lung disease) in affected individuals

HOW LEVOSALVAC DUO RESPULES WORKS
LEVOSALVAC DUO RESPULES provides ease in breathing from bronchospasm (constricted airway muscles), where Ipatropium and Levosalbutamol work together to relax airway muscles which results in widening of airways providing relief from obstructive airflow and easy in breathing from bronchospasm associated with chronic obstructive pulmonary disease in affected individuals.
DIRECTIONS FOR USE
LEVOSALVAC DUO RESPULES should be administered only by a nebulizer (with a face mask connected to an air compressor) under the direction of a physician. It is for inhalation use only. Remove the pouch and tear one respule. Twist the cap to open the respule. Squeeze the content into the reservoir of nebulizing chamber and discard the respule after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF LEVOSALVAC DUO RESPULES

COMMON

Headache, dizziness

Tremor, nervousness, pain

Cough, sore throat, local irritation

Dry mouth, upset stomach, nausea, constipation, diarrhoea, vomiting

Urinary tract infection

Leg cramps

Voice changes

Racing heartbeat, fast heart rate

UNCOMMON

Red itchy welts

Accommodation disturbances, narrow angle-glaucoma (increased eye pressure)

Fast heart rate

Spasm of larynx

Diffuse skin rash

RARE

Signs of anaphylactic reaction (life threatening allergic reaction) such as wheezing, faint, breathing difficulties, and/or fast heartbeat

Swelling of tongue/lips/face

Eye pain, dilate pupil

Irregular heartbeats

Urinary retention
Stop using LEVOSALVAC DUO RESPULES and contact your doctor immediately if you experience any of the following side effects:
Signs of paradoxical bronchospasm (sudden constriction of airways after using medicine) such as shortness of breath, coughing, and/or wheezing

Signs of sudden hypersensitivity reaction (immune mediated allergic reaction) such as red itchy welts, swelling of face/mouth/tongue, bronchospasm (tighten airways), and/or rash

Signs of significant cardiovascular effects measured by pulse rate, blood pressure, and/or other symptoms

HOW TO MANAGE SIDE EFFECTS
Dry mouth:
Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptomets worse.
Dizziness:
Try to rest andet enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Headache:
If LEVOSALVAC DUO RESPULES causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usuallyo away after the first week of taking LEVOSALVAC DUO RESPULES. If it lasts more than a week or severe, inform your doctor.
Nausea and vomiting:
Take LEVOSALVAC DUO RESPULES with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.
Constipation:
Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.
Diarrhoea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult and inform your doctor if the symptom worsens.
WARNING & PRECAUTIONS

PREGNANCY
LEVOSALVAC DUO RESPULES should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary.? Consult your doctor before using the medicine.
BREASTFEEDING
LEVOSALVAC DUO RESPULES should be used with caution in breastfeeding women only if necessary since it is not known whether the medicine pass through breast milk. Consult your doctor before using the medicine.
DRIVING AND USING MACHINES
Do not drive/operate machines if LEVOSALVAC DUO RESPULES affects your ability to drive/operate machines.
KIDNEY
LEVOSALVAC DUO RESPULES should be used with caution in patients with kidney problems such are renal impairment. Consult your doctor before using the medicine.
LIVER
LEVOSALVAC DUO RESPULES should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before using the medicine.
ALLERGY
Do not take LEVOSALVAC DUO RESPULES if you are allergic to ipratropium, levosalbutamol, atropine, and/or any other ingredients of the medicine.
LUNGS
LEVOSALVAC DUO RESPULES should be used with caution in patients with lung problems such as asthma. Consult your doctor before using the medicine.
HEART DISEASE
LEVOSALVAC DUO RESPULES should be used with caution in patients with heart problems such as coronary insufficiency, cardiac arrhythmias. Consult your doctor before using LEVOSALVAC DUO RESPULES.
OTHERS
Before using LEVOSALVAC DUO RESPULES inform your doctor if you:
Have high blood pressure

Have seizures

Suffer from hyperthyroidism (overactive thyroid)

Have diabetes

Have narrow anglelaucoma (increased eye pressure)

Suffer from prostatic hypertrophy (enlarged prostateland)

Suffer from bladder-neck obstruction.
Use in Paediatrics:
LEVOSALVAC DUO RESPULES is not recommended for use in children (aged less than 6 years). It should be used with caution in children and adolescents (aged 6 to 18 years). Consult your doctor before administering LEVOSALVAC DUO RESPULES.
Use ineriatrics:
LEVOSALVAC DUO RESPULES should be used with caution in elderly patients (aged above 65 years). Consult your doctor before using LEVOSALVAC DUO RESPULES.
INTERACTIONS
A. Drug-Drug interactions:
Before using LEVOSALVAC DUO RESPULES, inform your doctor if you are taking any of the following medicine:
Short acting bronchodilators (used to quickly relieve/stop sudden asthma symptoms) Ex. albuterol, levalbuterol

Medicines used to treat high blood pressure such as beta-adregenic/receptor blocking agents (Ex. propanolol, metoprolol, atenolol)

Diuretics (used to treat high blood pressure) Ex. chlorothiazide, chlorthalidone

Digoxin (used to treat irregular heartbeats)

Monoamine oxidase inhibitors/tricyclic antidepressants (medicines used to treat depression) Ex. selegiline, phenelzine, amitriptyline, imipramine

Anticholinergic agents (medicines used to block acetylcholine) Ex. atropine, benztropine
Overdosage:
If you or anyone else accidentally take too much of LEVOSALVAC DUO RESPULES, then consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are seizures, chest pain, high/low blood pressure, fast heartbeat, irregular heartbeat, nervousness, headache, tremor, dry mouth, pounding heartbeat, nausea, dizziness, fatigue, weakness, sleeplessness, hypokalaemia (low potassium level in blood), fast breathing, high fever, restlessness, hallucinations, confusion, and/or cardia arrest.
SYNOPSIS

Drug :?? Ipratropium bromide, Levosalbutamol

Pharmacological Category :?? Bronchodilator agents, Adrenergic beta-agonists

Therapeutic Indication :?? Bronchospasm associated with chronic pulmonary disease

Dosage Forms :?? Rotacap, Inhalation Capsule, Inhaler, Respules, Smartule, Mistpules, Transpule

MORE INFORMATION

Keep LEVOSALVAC DUO RESPULES out of reach of children

Store LEVOSALVAC DUO RESPULES above 25?C

FAQs ABOUT LEVOSALVAC DUO RESPULES
What is LEVOSALVAC DUO RESPULES used for?
LEVOSALVAC DUO RESPULES is used to treat bronchospasm (tightened airway muscles) associated with chronic obstructive pulmonary disease (inflammatory lung disease) in patients who require more than one bronchodilator (medication) to help them in easy of breathing.
What are the side effects of LEVOSALVAC DUO RESPULES?
The most common side effects of using LEVOSALVAC DUO RESPULES are headache, dizziness, nervousness, cough, sore throat, local irritation, dry mouth, nausea, and/or diarrhoea. Consult your doctor if any of these symptoms worsens.
How LEVOSALVAC DUO RESPULES works?
LEVOSALVAC DUO RESPULES provides ease in breathing from bronchospasm (constricted airway muscles), where Ipatropium and Levosalbutamol work together to relax airway muscles which results in widening of airways providing relief from obstructive airflow and easy in breathing from bronchospasm associated with chronic obstructive pulmonary disease in affected individuals.
How LEVOSALVAC DUO RESPULES is administered?
LEVOSALVAC DUO RESPULES should be administered only by a nebulizer (with a face mask connected to an air compressor) under the direction of a physician. It is for inhalation use only. Remove the pouch and tear one respule. Twist the cap to open the respule. Squeeze the content into the reservoir of nebulizing chamber and discard the respule after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Can LEVOSALVAC DUO RESPULES be used in pregnant and breastfeeding women?
Yes, LEVOSALVAC DUO RESPULES can be used but with caution in pregnant and breastfeeding women. ?Consult your doctor before using LEVOSALVAC DUO RESPULES.
REFERENCES
1. K.D. Tripathi. Anticholinergic Drugs and Drugs Acting on Autonomicanglia. Essentials of medical pharmacology. Seventh edition. 2013. Page- 116.
2. A S Hossain, U K Barua, C Roy, S R Sutradhar, I Rahman, Rahman. Comparison of salbutamol and ipratropium bromide versus salbutamol alone in the treatment of acute severe asthma. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in April 2013] [Accessed on 30th May 2022]?https://pubmed.ncbi.nlm.nih.gov/23715360/
3. Chemo Biological. DUOCOPID-3 RESPULES. [Accessed on May 30th May 2022]?https://chemobiological.in/duocopid-3-respules/
4. Lupin Limited. Salbair I Neb Transpules 0.63. [Accessed on May 30th May 2022]?https://www.lupin.com/our-products/product-finder/?searchkey=salbair
5.?JB Pharma. Dutaresp. [Accessed on May 30th May 2022]?https://jbpharma.com/our-therapies/
6.lenmark Pharma. NEBZMART. [Accessed on May 30th May 2022]?https://glenmark.b-cdn.net/gpl_pdfs/products/Glenmark Pharmaceuticals Ltd- Product List as on October 2022.pdf
7. CiplaMed. DUOLIN LD Respules. ?[Revised in August 2020] [Accessed on May 30th May 2022]?https://www.ciplamed.com/content/duolin-ld-respules
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