MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s act as a smooth muscle relaxant, possibly by blocking calcium-mediated contraction, decreasing acetylcholine release from neuromuscular junctions, and reducing histamine-induced airway spasm.
Side effects
Major & minor side effects for MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s

Difficulty in breathing

Swelling of eyelids, face, lips

Itching and rash

Dizziness and Drowsiness

Pain at the injection site

Muscle weakness

Excessive thirst

Slurred speech

Uses of MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s
What is it prescribed for?

Hypomagnesemia
This medicine is used to correct the MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s levels in patients with low MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s levels in the body when the patient is not able to tolerate oral supplements.

Toxemia of Pregnancy
This medicine is used for the prevention and control of seizures associated with pre-eclampsia (a pregnancy complication characterized by increased blood pressure and protein in the urine) and eclampsia (a condition where there is an occurrence of seizures in pregnant women with severe preeclampsia).

Atrial tachycardia
This medicine is used for the treatment of patients with atrial tachycardia, a type of heart rhythm abnormality characterized by a constant rate of more than 100 beats per minute.

Seizures
This medicine is used for the control of seizures.

Concerns

Frequently asked questions

Onset of action
Anticonvulsant effect: The effect of this medicine can be observed within1 hour of intramuscular administration of dose and immediately after intravenous administration of dose.

Duration of Effect
Anticonvulsant effect: The effect of this medicine lasts for an average duration of 3 to 4 hours after intramuscular administration and 30 minutes after intravenous administration of the dose.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s or any other inactive ingredients present in the formulation.

Hypermagnesemia
This medicine is not recommended for use in patients with hypermagnesemia (high blood MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s levels) due to the increased risk of adverse effects.

Hypercalcemia
This medicine is not recommended for use in patients with hypercalcemia (high levels of calcium in the blood) due to the risk of worsening of the patient’s condition.

Myocardial damage
This medicine is not recommended for use in patients with myocardial damage due to the risk of worsening of the patient’s condition.

Diabetic coma
This medicine is not recommended for use in patients with diabetic coma due to the risk of worsening of the patient’s condition.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

General Warnings

Hypermagnesaemia
Use of this medicine may increase the MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s levels in the blood. The risk is especially higher in patients suffering from kidney diseases. Report any symptoms such as flushing of the skin, increased thirst, difficulty in breathing, changes in heart rate, etc. to the doctor immediately. Close monitoring of MAGNESIUM SULPHATE 500mg|ml Injection 10mlx1s levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Other uses
Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Liver impairment
This medicine should be used with caution in patients with liver impairment due to the risk of worsening of the patient’s condition. Close monitoring of liver function is recommended while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Dosage

Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Atracurium moderate

Raltegravir moderate

Nifedipine moderate

Cisatracurium moderate

Disease interactions

severe
This medicine should be used with caution in patients suffering from kidney function impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

General Instructions

This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

References

webmd.com –
Magnesium Sulphate [Internet].
Available from: https://www.webmd.com/drugs/2/drug-169449/magnesium-sulfate-oral/detailsq
[cited 7/8/2020].

sciencedirect.com –
Magnesium Sulphate [Internet].
Available from: https://www.sciencedirect.com/topics/medicine-and-dentistry/magnesium-sulfate#:~:text=Magnesium%20sulfate%20(MgSO4)%20can%20act,reducing%20histamine%2Dinduced%20airway%20spasm.
[cited 7/8/2020].