Medicarpine 2.00% Eye Drops 5 ml works by stimulating certain nerves to increase the amount of saliva you produce, making it easier and more comfortable to speak and swallow.
Side effects
Major & minor side effects for Medicarpine 2.00% Eye Drops 5 ml

Increased sweating

Tremors

Nausea and vomiting

Diarrhea

Troubled breathing

Watering of mouth

Eye pain

Blurred vision

Headache

Chills

Runny Nose

Frequent urination

Dizziness

Weakness

Heartburn

Stomach pain

Fast or slow heartbeat rare

Uses of Medicarpine 2.00% Eye Drops 5 ml
What is it prescribed for?

Xerostomia
This medicine is used for the treatment of abnormal dryness of the mouth (xerostomia) in patients undergoing radiotherapy for head and neck cancer and in patients with a Sjogren’s syndrome, condition that affects the immune system and causes dryness of mouth and eyes.

Intraocular hypertension
The ophthalmic form of this medicine is used to reduce fluid pressure inside the eyes for patients suffering from intraocular hypertension.

Open angle Glaucoma
The ophthalmic form of this medicine is used in the treatment of open-angle glaucoma, a condition characterized by progressive damage to the optic nerve that may eventually lead to vision loss.

Narrow-angle glaucoma
The ophthalmic form of this medicine is used in the treatment of narrow-angle glaucoma, a condition that occurs suddenly when the iris is pulled or pushed forward and there is a fluid build up behind the iris.

Production of miosis
The ophthalmic and intracameral (injection into the eye chamber) forms of this medicine are used for the production of miosis (excessive constriction of the pupil of the eye) prior to and during ophthalmic surgeries as necessary.

Concerns

Frequently asked questions

Onset of action
The effect of the oral form of this medicine can be observed within 20 minutes of administration of the dose. The effect of the ophthalmic form of this medicine can be observed within 10 to 30 minutes of administration of the dose. The effect of the intracameral form of this medicine (injection into the eye chamber) is rapid.

Duration of Effect
The effect of the oral form of this medicine lasts for an average duration of 3 to 5 hours. The effect of the ophthalmic form of this medicine lasts for an average duration of 4 to 8 hours. The amount of time for which the intracameral (injection into the eye chamber) form of this medicine remains active is not clinically established.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition. If the medicine is used, monitor the infant closely for any adverse effects.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Medicarpine 2.00% Eye Drops 5 ml or any other inactive ingredients present along with this medicine.

Asthma
This medicine is not recommended for use in patients with uncontrolled asthma since it may worsen the patient’s condition.

Uveitis
This medicine is not recommended for use in patients suffering from uveitis since it may worsen the patient’s condition.

Undesirable pupillary constriction
This medicine is not recommended for use where pupillary constriction is undesirable such as acute iritis, anterior uveitis, etc.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition. If the medicine is used, monitor the infant closely for any adverse effects.

General Warnings

Contact lens
This ophthalmic form of this medicine is not recommended for use if you are wearing soft contact lenses in your eyes. The lens should be removed prior to administration and can be reinserted after 10 to 15 minutes of administration of the dose.

Driving or operating machines
This medicine may cause blurred vision and dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dehydration
This medicine should be used with caution in patients who are known or expected to sweat excessively due to the increased risk of dehydration. Patients are advised to drink an adequate amount of water or liquids to maintain hydration.

Peptic ulcer
The oral form of this medicine should be used with caution in patients with peptic ulcer disease due to the increased risk of worsening of the patient’s condition. Appropriate patient education, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Renal impairment
The oral form of this medicine should be used with caution in patients with renal impairment due to the increased risk of severe adverse effects. Close monitoring of renal function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Cardiovascular diseases
The oral form of this medicine should be used with caution in patients with cardiovascular diseases due to the increased risk of worsening of the patient’s condition. Appropriate patient education, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Pulmonary diseases
The oral form of this medicine should be used with caution in patients suffering from lung diseases such as controlled asthma, chronic bronchitis, or chronic obstructive pulmonary disease due to the increased risk of worsening of the patient’s condition. Appropriate patient education, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Dosage

Missed Dose
Oral form: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Eye drops: Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose
Oral form and eye drops: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Atropine moderate

Ipratropium moderate

Loxapine moderate

Atenolol moderate

Clozapine moderate

Disease interactions

severe
This medicine should be used with caution in patients with risk factors for retinal detachment such as old age, retinal degenerative changes or other retinal disorders, aphakia, prior cataract extraction, or a history of severe myopia or retinal detachment due to the increased risk of retinal detachment. Fundus examination is advised in all patients before starting therapy with this medicine. Replacement with a suitable alternative may be required based on the clinical condition of the patient.

severe
This medicine is not recommended for use in patients with uveitis due to the increased risk of worsening of the patient’s condition. Replacement with a suitable alternative should be considered under your doctor’s supervision.

moderate
This medicine should be used with caution in patients with or predisposed to cataracts due to the increased risk of worsening of the patient’s condition. Replacement with a suitable alternative may be required based on the clinical condition of the patient.

General Instructions

Oral form: Take this medicine with or without food. Do not consume in larger amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Eye drops: Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Injection: This medicine is administered by a qualified healthcare professional in the hospital setting. Inform the doctor if you have a known allergy to this medicine. Report to the doctor all your current medicines including herbs and supplements as well as all your medical conditions before receiving this medicine.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

References

webmd.com –
Pilocarpine [Internet].
Available from: https://www.webmd.com/drugs/2/drug-78603/pilocarpine-oral/details
[cited 14/7/2020].