This medicine works by inhibiting the action of certain specific neurotransmitters in the brain and specific regions of the stomach and the intestine.
Side effects
Major & minor side effects for Motivo tablet 25 mg 2_10?s

Drowsiness

Breast tenderness

Irregular menstrual periods

Gynacomastia severe

Cosntipation

Abdominal pain and cramps

Weight gain

Sleeplessness

Unusual tiredness and weakness

Increased salivation

Decrease in libido

Fever severe

Excessive sweating severe

Change in heart rate

Uses of Motivo tablet 25 mg 2_10?s
What is it prescribed for?

Gastroesophagal Reflux Disease
This medicine is used for the treatment of gastroesophagal reflux disease marked by increased irritation of the stomach caused by bile and acid.

Irritable bowel syndrome
This medicine is used for the treatment of irritable bowel syndrome marked by persistent stomach pain, flatulence, diarrhea, or constipation.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed within 1-2 hours of oral administration.

Duration of Effect
The effect of this medicine lasts for an average duration of 5-8 hours upon oral administration.

Safe with Alchohol?
Avoid or limit the uptake of alcohol while taking this medicine as the risk of adverse effects are increasingly high. Contact your doctor if an excess of drowsiness is experienced.

Is it habit forming?
No habit forming tendencies were reported.

Usage in pregnancy?
Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.

Usage while breast-feeding?
Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

When not to use?

Allergy
This medicine is not recommended for use if you have a known history of allergy to Motivo tablet 25 mg 2_10?s or any other component present with it.

Epilepsy
This medicine is not recommended for use if you suffer from epilepsy or have a history of convulsions.

Bipolar disorder
This medicine is not recommended for use in patients suffering from bipolar disorder marked by frequent episodes of anxiety, agitation, depression, hallucinations etc.

Pheochromocytoma
This medicine is not recommended for use in patients having a tumor of the adrenal glands that causes a life threatening rise in blood pressure.

Gastrointestinal perforation
This medicine is not recommended for use if you have a condition where the food pipe and the gut is bleeding, obstructed, and perforated.

Breast cancer
This medicine is not recommended for use if you have been diagnosed with breast cancer (malignant mastopathy).

Warnings

Warnings for special population

Pregnancy
Use of this medicine during pregnancy is not recommended unless absolutely necessary. It is advised to use this medicine only when the benefits outweigh the risks involved.

Breast-feeding
Use of this medicine by breastfeeding women is not recommended. However, if it is absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor before using this medicine.

General Warnings

Heart disease
This medicine should be used with caution in patients having a history of stroke, blood clotting disorders or other ailments of the heart and blood vessels.

Diabetes
This medicine should be used with caution in patients who are suffering from diabetes or are exposed to the risk factors.

Hypokalemia
This medicine should be used with caution in patients having low potassium levels in the body. It is recommended to initiate treatment with Motivo tablet 25 mg 2_10?s only after the potassium deficit is corrected.

Breast cancer
This medicine is not recommended for use if the patient is suspected to have breast cancer associated with abnormally high levels of prolactin in the body.

Drowsiness
This medicine is known to cause moderate to severe drowsiness and may the ability to perform tasks that require a high level of mental alertness. It is advised to refrain from driving or operating any heavy machinery after consuming this medicine.

Leukopenia
This medicine is not recommended for use in patients who have a decreased white blood cell count characterized by frequent infections, fever with chills, sore throat, and mouth ulcers.

Use in elderly
This medicine should be used with caution in the elderly as the risk of side effects are increasingly high. Appropriate dose adjustments should be made based on the response of the patients.

Menstrual abnormalities
Use of this medicine has been associated with abnormalities in menstrual period. Contact your doctor if the regular periods are excessively delayed.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

Overdose
Contact a doctor if an overdose with Motivo tablet 25 mg 2_10?s is suspected. Symptoms of an overdose may include excessive drowsiness, fall in blood pressure, agitation, coma etc.

Interactions
Interaction with Medicines

Diltiazem moderate

Pregabalin moderate

Sucralfate moderate

Tramadol severe

Aluminium Hydroxide/Magnesium Hydroxide moderate

Ipratropium moderate

Disease interactions

moderate
This medicine should be used with caution in patients suffering from a disease of the heart and blood vessels. You may require an adjusted dose and safety monitoring to safely use this medicine.

severe
This medicine should be used with extreme caution in patients suffering from perforation and bleeding of the stomach and the intestine. Report any instance of fever with chills, nausea, vomiting, presence of blood in stool to the doctor.

severe
This medicine should not be used in patients having an abnormal level of the hormone prolactin. Breast cancer due to a high level of prolactin should be ruled out before treatment with this medicine is initiated.

severe
Use of this medicine is not recommended if the patient suffers from Neuroleptic malignant syndrome. Introduction or reintroduction of this medicine should be done with caution in patients having a known history of this syndrome.

moderate
This medicine should be used with caution if you have asthma. Report any instances of difficulty in breathing, wheezing, chest pain etc to the doctor immediately.

Lab interactions

General Instructions

Take Motivo tablet 25 mg 2_10?s as instructed by the doctor. This medicine should be taken at least half an hour before food. Do not take this medicine in larger or smaller quantities than recommended. It is advised to take plenty of water while taking this medicine.

Other details

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

References

pubchem.ncbi.nlm.nih.gov –
Levosulpiride [Internet].
Available from: https://pubchem.ncbi.nlm.nih.gov/compound/688272#section=Top
[cited 11 september 2019].
2019-09-07

practo.com –
Levosulpiride [Internet].
Available from: https://www.practo.com/medicine-info/levosulpiride-163-api
[cited 11 september 2019].
16 Nov 2017

drugbank.ca –
Sulpiride [Internet].
Available from: https://www.drugbank.ca/drugs/DB00391
[cited 11 september 2019].
September 02, 2019