Specification
OLSONG CT 20mg Tablet 10?s
?Chlorthalidone 12.5 mg Olmesartan 20 mg
INTRODUCTION:-
OLSONG CT 20MG is a combination of Chlorthalidone and Olmesartan which belongs to theroup of medicines called Thiazide diuretics and Angiotensin-II receptor antagonists respectively. OLSONG CT 20MG is indicated for the treatment of essential hypertension. Essential hypertension (also known as primary hypertension) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the walls of blood vessels supplying various important organs. It occurs without any known secondary cause and if remains untreated it can lead to severe problems such as heart attack, heart or kidney failure, stroke, or even blindness.
Olmesartan is an Angiotensin-II receptor antagonist that effectively reduces blood pressure by blocking the actions of Angiotensin ? II (a substance that causes narrowing of blood vessels and increase in blood pressure) at the angiotensin type-I receptors and chlorthalidone is a thiazide diuretic that acts by increasing urinary excretion of sodium and water, thus reducing blood volume followed by a marked decrease in blood pressure. Along treatment with OLSONG CT 20MG follow the lifestyle modifications (such as losing weight, quitting smoking or alcohol intake) as advised by your physician along with a healthy balanced diet and a regular physical activity (such as walking or swimming).
During course of the treatment with OLSONG CT 20MG, your doctor might regularly check your blood pressure, kidney function and electrolyte balance to avoid the risk of side effects. Avoid eatingrapefruit or consumingrapefruit juice while taking OLSONG CT 20MG as it could potentiate the blood pressure lowering effect of this medicine. Before taking OLSONG CT 20MG, inform your doctor if you have diabetes, liver, kidney, or heart disease as a precaution.
OLSONG CT 20MG is strictly not recommended for use in pregnant or breastfeeding women as it could cause serious harm to the baby. The most common side effects of taking OLSONG CT 20MG are headache, dizziness, tiredness, nausea, stomach pain, lack of appetite or electrolyte imbalance. Consult your doctor if any of the symptoms worsen.
USES OF OLSONG CT 20MG:-
Treats essential hypertension
HOW OLSONG CT 20MG WORKS:-
OLSONG CT 20MG effectively reduce elevated blood pressure where olmesartan acts by blocking the actions of Angiotensin ? II (a substance that causes narrowing of blood vessels and increase in blood pressure) at the angiotensin type-I receptors of the vascular smooth muscle and chlorthalidone acts by increasing the urinary excretion of sodium and water by inhibiting sodium-chloride reabsorption in the kidneys, thus leading to a marked decrease in blood pressure.
DIRECTIONS FOR USE:-
Take OLSONG CT 20MG as advised by your physician. Swallow OLSONG CT 20MG with alass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF OLSONG CT 20MG:-
COMMON
Headache and dizziness
Nausea, indigestion, diarrhea, stomach pain
Tiredness
Sore throat, runny nose, flu-like symptoms, cough
Chest pain, back pain, joint pain
Urinary tract infection
Swelling of the feet, ankles, hands, or arms
Blood in urine
Signs of low potassium levels in blood (muscle weakness or twitching or abnormal heartbeat)
Signs of high uric acid levels in blood (pain and swelling in joints)
Increased blood cholesterol levels
Signs of low sodium levels in blood (tiredness, confusion, muscle twitching, fits or coma)
Signs of low levels of magnesium in blood (muscle spasm, shaking, nausea, tiredness)
High blood sugar levels (tiredness, weakness or feeling thirsty)
Skin rash
Orthostatic hypertension (feeling dizzy while standing up)
Loss of appetite
Impotence in men
UNCOMMON
Mood changes, anxiety, depression
Sleeplessness
Cough, dry mouth
Vomiting
Hair loss
Increased sweating
Red patches, itchy skin
Skin discoloration
Increased or decrease in weight
Pain,eneral discomfort
Enlarged breasts in men (gynecomastia)
Increased urination, urinary urgency (at night)
Disorder in passing urine
Decrease in blood platelets (easy bruising or bleeding)
RARE
Muscle cramps
Kidney problems
Signs of increased blood potassium levels (stomach pain, diarrhea, irregular heartbeat)
Confusion
Signs of increased calcium in blood (agitation, sore eyes, abdominal pain)
Worsening of diabetes
Jaundice (yellowing of the skin or eyes)
Photosensitivity
Breathing problems, palpitations, and fainting
Pins and needles
Constipation
Changes in WBC count (repeated infections, fever, mouth ulcers)
Stop taking OLSONG CT 20MG and contact your doctor immediately if you experience any of the following side effects:
Severe allergic reactions (such as skin rash, itching, swelling of the face, mouth and/or larynx)
Severe hypotension (low blood pressure) with light-headedness or fainting
HOW TO MANAGE SIDE EFFECTS:-
Nausea and vomiting:
Try to take OLSONG CT 20MG with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Dizziness:
Try to rest and relax.et enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Constipation:
Eat fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom did not improve on its own.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.
Loss of appetite:
Eat when you are hungry. Try to eat smaller meals more often than usual. Snack only when you?re hungry. Try to have a nutritious snack that is high in calories and protein, such as dried fruit and nuts.
WARNING & PRECAUTIONS:-
PREGNANCY
OLSONG CT 20MG is not recommended for use in pregnant women because it can cause serious harm to the developing fetus. Consult your doctor before taking OLSONG CT 20MG.
BREASTFEEDING
OLSONG CT 20MG is not recommended for use in breastfeeding women because it passes through breast milk and could cause serious harm to the baby. Consult your doctor before taking OLSONG CT 20MG.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machines if you experience dizziness, sleepiness, or tiredness. Consult your doctor before taking OLSONG CT 20MG.
ALCOHOL
Avoid consumption of alcohol while taking OLSONG CT 20MG, as it could aggravate your existing disease condition. Consult your doctor before taking OLSONG CT 20MG.
KIDNEY
OLSONG CT 20MG is not recommended for use in patients with severe kidney problems, kidney failure, lack of urine, kidney stones and should be used with caution in patients with kidney problems. Kindly consult your doctor before taking OLSONG CT 20MG.
LIVER
OLSONG CT 20MG is not recommended for use in patients with severe liver disease, jaundice (yellowing of skin and eyes) or biliary obstruction (problem in bile drainage)?and should be used with caution in patients with liver disease. Kindly consult your doctor before taking OLSONG CT 20MG.
ALLERGY
Do not take OLSONG CT 20MG if you are allergic to Chlorthalidone, Olmesartan or any sulphonamide derivatives (Ex. sulfadiazine, sulfamethazine).
HEART DISEASE
OLSONG CT 20MG is not recommended for use in patients with heart failure or attack, cardiogenic shock, narrowing of the aortic heart valve, and severe low blood pressure. It should be used with caution in patients with coronary or cerebral arteriosclerosis and obstructive hypertrophic cardiomyopathy (heart muscle becomes abnormally thick). Kindly consult your doctor before taking OLSONG CT 20MG.
OTHERS:-
OLSONG CT 20MG is not recommended for use if you have:
Severe fluid-electrolyte imbalance (such as low levels of potassium, sodium, or calcium in blood)
A history ofout
Untreated Addison?s disease (an endocrine disorder of adrenallands)
Primary aldosteronism (a disorder due to increased aldosterone production)
Diabetes or diabetes related kidney problem (Ex. diabetic nephropathy)
Before taking OLSONG CT 20MG, inform your physician if you:
Have high blood cholesterol levels
Are on a low-sodium diet
Have severe vomiting or diarrhea
Have hyperkalemia (increased blood potassium levels)
Have metabolic acidosis (increase in plasma acidity)
Have a condition that involves cellular breakdown or damage (Ex. acute limb ischemia (decrease blood flow to lower limb), rhabdomyolysis (severe muscle injury), extended trauma)
Have hyperparathyroidism (overactive parathyroidland)
Have recently had an anesthetic
Use in pediatrics:
OLSONG CT 20MG is not recommended for use in children and adolescents (below 18 years) due to lack of safety data. Kindly consult your doctor before taking OLSONG CT 20MG.
Use ineriatrics:
OLSONG CT 20MG should be used with extreme caution in elderly patients (aged 65 years or above). Proper dose adjustments and careful monitoring of blood pressure, kidney function and electrolyte balance are required in such patients. Consult your doctor before taking OLSONG CT 20MG.
INTERACTIONS:-
A. Drug-Drug interactions:
Before taking OLSONG CT 20MG inform to your doctor, if you are taking any of these medicines:
Other medicines used to reduce hypertension and other heart problems such as ACE inhibitors (Ex. captopril, enalapril), angiotensin receptor blockers (Ex. losartan, valsartan), calcium channel blockers (Ex. nifedipine, diltiazem, verapamil), beta-blockers (Ex. atenolol, propranolol), vasodilators (Ex. nitroglycerin, bosentan), digoxin, methyldopa,uanethidine or aliskiren
Lithium (used to treat depression or other mental illness)
Non-steroidal anti-inflammatory drugs (used to treat pain or inflammation) Ex. indomethacin
Simvastatin, colesevelam and cholestyramine (used to control high blood cholesterol levels)
Antacids (used to neutralize stomach acid) Ex. aluminium hydroxide, magnesium hydroxide
Ketoconazole, itraconazole or amphotericin (used to treat fungal infections)
Protease inhibitors (used to treat HIV infections) Ex. ritonavir, indinavir, nelfinavir
Certain antibiotics (used to treat bacterial infections) Ex. rifampicin, erythromycin, clarithromycin
Hypericum perforatum (an herbal medicine used to treat depression)
Dantrolene (used to treat muscle spasticity)
Immunosuppressant (used to suppress immune function and preventraft rejection) Ex. tacrolimus, sirolimus, temsirolimus, everolimus, or cyclosporine
Adrenocorticotropic hormone (used to treat various endocrine disorders)
Corticosteroids (used to treat allergic or inflammatory diseases and immune reactions) such as prednisolone or betamethasone
Anticholinergics (used to reduce stomach spasms or cramps) such as atropine, biperiden or hyoscine butyl bromide
Cyclophosphamide or methotrexate (used to treat certain forms of cancer)
Salbutamol or formoterol (used to treat asthma)
Amantadine (a medicine used to treat viral infections or Parkinson?s disease)
Allopurinol (a medicine used to treatout)
Carbenoxolone (a medicine used to treat stomach ulcers)
Calcium salts or vitamin D (used as a supplement)
Medicines used to treat diabetes (Ex. insulin, chlorpropamide orlibenclamide)
Diazoxide (used to manage low bloodlucose levels)
Medicines that can alter blood potassium levels such as potassium-sparing diuretics (Ex. spironolactone, acetazolamide), salt substitutes containing potassium (Ex. losartan potassium) and heparin sodium
B. Drug-Food interaction:
OLSONG CT 20MG can be taken with or without food. Avoid consumption ofrapefruit orrapefruit juice while taking OLSONG CT 20MG as it could cause severe decrease in blood pressure.
Overdosage:
If you or anyone else accidentally take too much of OLSONG CT 20MG, contact your doctor immediately oro to a hospital straight away. Overdosage symptoms of OLSONG CT 20MG might include dizziness, excess sleepiness, nausea, hypovolemia, low blood pressure, and electrolyte disturbances associated with cardiac arrhythmias and muscle spasms.
SYNOPSIS:-
Drug :?? Chlorthalidone, Olmesartan
Pharmacological Category :?? Thiazide diuretics, Angiotensin-II receptor antagonists
Therapeutic Indication :?? Essential hypertension
Dosage Forms :?? Tablet
MORE INFORMATION:-
Keep OLSONG CT 20MG out of reach of children
Store OLSONG CT 20MG at room temperature
FAQs ABOUT OLSONG CT 20MG:-
Can OLSONG CT 20MG be taken during pregnancy?
No. OLSONG CT 20MG is strictly not recommended for use in pregnant women because it can cause serious harm to the developing fetus. If you are planning for pregnancy, consult your doctor before taking OLSONG CT 20MG.
Can I consume alcohol while taking OLSONG CT 20MG?
No. Avoid consumption of alcohol while taking OLSONG CT 20MG, as it could aggravate your existing disease condition and increase the risk of serious complications such as heart attack, stroke, or kidney problems.
Can OLSONG CT 20MG be used in chronic kidney disease?
No. OLSONG CT 20MG is not recommended for use in patients with severe kidney disease such as chronic kidney disease. Kindly consult your doctor before taking OLSONG CT 20MG.
Can OLSONG CT 20MG causeout?
Yes. OLSONG CT 20MG can increase the levels of uric acid in blood in some individuals, and so caution should be exercised among patients with kidney disease or a previous history ofout. Kindly consult your doctor before taking OLSONG CT 20MG.
Can OLSONG CT 20MG cause leg swelling?
Yes. OLSONG CT 20MG can cause swollen ankles, feet, legs, hands, or arms, although not everybodyets them and so caution should be exercised among patients with kidney or heart disease. Kindly consult your doctor before taking OLSONG CT 20MG.
What to do If I forget to take OLSONG CT 20MG?
You should take OLSONG CT 20MG immediately when you remember. If it is time for your next dose of OLSONG CT 20MG skip the dose and follow your regular dose schedule. Do not double the dose of to match up your missed dose.
REFERENCES:-
1. KD. Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page ? 559 & 561-562.
2. Thomas Michel and Brian B. Hoffman. Treatment of Myocardial ischemia and Hypertension.oodman &ilman?s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page ? 767-770 & 778.
3.erald. Briggs and Roger K. Freeman. C. and O. A referenceuide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page ? 760 & 2852.
4. Dr.. Chitti Pantulu, Dr. Avinash Shende, Dr. Prathmesh Mule and Dr. A. A. Faruqui. Evaluation of efficacy and safety of oral olmesartan and chlorthalidone fixed dose combination in the management of hypertension in Indian Patients. International journal of current research. [Accessed on 23rd October 2021]?http://www.journalcra.com/article/evaluation-efficacy-and-safety-oral-olmesartan-and-chlorthalidone-fixed-dose-combination
5. Elena Filipova, Stela Dineva , Katya Uzunova, Velichka Pavlova, Krassimir Kalinov and Toni Vekov. Combining angiotensin receptor blockers with chlorthalidone or hydrochlorothiazide ? which is the better alternative? A meta-analysis. Systematic reviews. BMC. 2020. [Accessed on 23rd October 2021]?https://d-nb.info/1219505919/34
6. TORRENT PHARMACEUTICALS LTD. OLSAR CH. Torrentian.com. [Revised in February 2021]?[Accessed on 23rd October 2021]?https://www.torrentian.com/pisheet/Upload/PI_Sheet/3004.pdf
USEFUL DIAGNOSTIC TESTS:-
Kidney function test
PRODUCT DETAILS:-
Net Qty
1 N
Item Weight
17.5
Ingredient
CHLORTHALIDONE 12.5 mg OLMESARTAN MEDOXOMIL 20 mg
Hsn Code
30049079
Additional information
Weight
17.5 g
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