Description

Ondansetron injection is used to stop nausea and vomiting brought on by cancer treatments (chemotherapy or radiation), especially high-dose cisplatin. Additionally, following surgery, this medication is used to both prevent and cure postoperative nausea and vomiting.
Indications

Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.

Prevention of nausea and vomiting associated with radiotherapy in patients receiving total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen.
Dosage

Chemotherapy – Induced Nausea & Vomiting
Adults

IV Dose 32mg IV or 150 mcg per kg of body weight.

Children 150 mcg per kg body weight (6 months to 18 years).

For prevention of postoperative nausea and vomiting
Adults

IV Dose 4 mg IV over a period of thirty sec. to five min. (Given just before anesthesia).

Children (1 month to 12 years) 100mcg/kg of weight for children weighing 40 kg or less, or 4 mg for children weighing over 40 kg.