This medicine works by stimulating the absorption of calcium and phosphorus from the intestines. It also promotes reabsorption of calcium from the bones and the kidneys.
Side effects
Major & minor side effects for One-Alpha capsule 0.5 mcg 30?s

Headache

Drowsiness

Irregular heart beat severe

Constipation

Nausea and Vomiting

Fever

Increased thirst

Skin rash and itching

Bone and joint pain severe

Muscle pain and weakness severe

Increased calcium levels

Decreased libido

Uses of One-Alpha capsule 0.5 mcg 30?s
What is it prescribed for?

Hypocalcemia
This medicine is used to treat a deficiency of calcium in the blood (low blood calcium levels).

Hypophosphatemic vitamin D-resistant rickets and osteomalacia
This medicine is used to treat rickets and osteomalacia (bone diseases characterized by bone softening and weakening) associated with low levels of phosphate ions in the blood.

Renal Osteodystrophy

Osteomalacia and Rickets

Concerns

Frequently asked questions

Onset of action
The amount of time taken for this medicine to show its effect is subject to variations based on the route of administration. Peak concentrations are achieved after 12 hours of oral administration and 4 hours of intravenous administration (injection).

Duration of Effect
This effect of this medicine lasts for an average duration of 2 to 7 days.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to One-Alpha capsule 0.5 mcg 30?s or any other inactive ingredients present along with it.

Hypercalcemia
This medicine is not recommended for use in patients with elevated levels of calcium in the blood due to the increased risk of worsening of the patient’s condition.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.

General Warnings

Hypercalcemia
This medicine is not recommended for use in patients with elevated levels of calcium in the blood (hypercalcemia). Blood calcium levels should be checked before beginning therapy with this medicine. Close monitoring of blood calcium levels is recommended during treatment with this medicine as well. Appropriate corrective measures and/or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hypervitaminosis D
This medicine is not recommended for use in patients with high levels of Vitamin D in the body. Appropriate corrective measures, dose adjustments, and/or replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Other Vitamin D products
This medicine is not recommended for use in patients receiving other supplements or drugs containing vitamin D as an ingredient due to the increased risk of serious adverse effects. It is advised that you report to the doctor all your current medicines including any herbs and supplements before beginning therapy with this medicine.

Cardiovascular diseases
This medicine should be used with caution in patients suffering from cardiovascular diseases due to the increased risk of worsening of the patients’ condition. This risk is especially higher if the medicine is used for a prolonged period of time. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Dosage

Missed Dose
Oral forms: Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not use extra medicine to make up for the missed dose. Injections: Since this medicine is usually administered in the clinical/hospital setting by a qualified healthcare professional, the likelihood of a missed dose is very low. If you miss an appointment for receiving this medicine, contact your doctor immediately for further instructions.

Overdose
Discontinue the use of this medicine and consult your doctor immediately if an overdose is suspected. Consumption of Vitamin D rich food or supplements along with this medicine may also cause an overdose.

Interactions
Interaction with Medicines

Hydrochlorothiazide moderate

Cholestyramine moderate

Magnesium/Aluminum containing medicines moderate

Laxatives moderate

Digoxin severe

Phenytoin moderate

Carbamazepine moderate

General Instructions

Oral forms: Use this medicine exactly as prescribed by the doctor. Do not use in larger or smaller amounts than advised. Injections: This medicine is usually administered in the hospital/clinical setting by a qualified healthcare professional. Report any undesirable side effects to the doctor immediately. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

References

practo.com –
Alfacalcidol [Internet].
Available from: https://www.practo.com/medicine-info/alfacalcidol-1640-api
[cited 14 september 2019].
2 Aug 2018

pubchem.ncbi.nlm.nih.gov –
Alfacalcidol [Internet].
Available from: https://pubchem.ncbi.nlm.nih.gov/compound/alfacalcidol#section=Top
[cited 14 september 2019].
2019-09-07

sciencedirect.com –
Alfacalcidol [Internet].
Available from: https://www.sciencedirect.com/topics/neuroscience/alfacalcidol
[cited 14 september 2019].