Oxytocin Injection 10 IU 100 Ampx1 mL works by increasing the concentration of calcium inside muscle cells that control contraction of the uterus. Increased calcium increases contraction of the uterus.
Side effects
Major & minor side effects for Oxytocin Injection 10 IU 100 Ampx1 mL

Nausea and Vomiting

Headache

Irregular heartbeat

Low blood pressure

Convulsions

Shortness of breath rare

Abdominal cramps

Uses of Oxytocin Injection 10 IU 100 Ampx1 mL
What is it prescribed for?

Induction of labor
This medicine is used for relaxing and softening the cervix and induce uterine contractions for the induction of labor.

Augmentation of labor
This medicine is used for the augmentation of labor by inducing uterine contractions when poor uterine contractions are assessed or medically necessary.

Postpartum bleeding
This medicine is used for the control of postpartum hemorrhage (bleeding).

Termination of pregnancy
This medicine is used for the termination of pregnancy by inducing uterine contractions and expelling the fetus out.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed immediately after the administration of the dose.

Duration of Effect
The effects of this medicine last up to 2 to 3 hours after an intramuscular administration and 1 hour after an intravenous administration.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
Use of this medicine is not recommended for pregnant women other than for the indicated uses such as the induction of labor and termination of pregnancy. Otherwise, the risk of birth defects, abortion, and other abnormalities are very high.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Oxytocin Injection 10 IU 100 Ampx1 mL or any other inactive ingredients present in the formulation.

Hypertonic uterine patterns
This medicine is not recommended for use in case of hypertonic uterine patterns (a complication of labor induction).

Fetal distress
This medicine is not recommended for use in case of fetal distress where delivery is not about to happen.

Cord presentation or prolapse
This medicine is not recommended for use in conditions where vaginal delivery is not appropriate such as cord presentation or prolapse, Vasa Previa, total placenta previa, etc.

Cephalopelvic disproportion
This medicine is not recommended for use in case of cephalopelvic disproportion, a pregnancy complication where the pelvis is inadequate to allow the fetus to easily fit through the pelvic opening.

Cesarean section
This medicine is not recommended for patients who have a history of cesarean section due to the increased risk of adverse effects.

Warnings

Warnings for special population

Pregnancy
Use of this medicine is not recommended for pregnant women other than for the indicated uses such as the induction of labor and termination of pregnancy. Otherwise, the risk of birth defects, abortion, and other abnormalities are very high.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

General Warnings

For hospital use only
This medicine should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities.

Uncontrolled hypertension
This medicine should be used with caution in women suffering from uncontrolled hypertension due to the risk of worsening of the condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cerebrovascular dysfunction
This medicine should be used with caution in women with cerebrovascular dysfunction due to the risk of worsening of the condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Volume overload
This medicine may cause volume overload and water intoxication upon administration. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Uterine rupture
This medicine has been associated with cases of uterine rupture when used for labor induction in some cases. Caution is advised while using this medicine if the patient is in the late thirties and beyond or the delivery is cesarean.

Dosage

Missed Dose
Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions
Interaction with Medicines

Phenylephrine moderate

Dinoprostone severe

Atracurium moderate

Dopamine moderate

Midodrine moderate

General Instructions

This medicine should be administered only by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities. Detect whether the patient is allergic to this medicine before initiating the treatment.

Other details

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

References

medicinenet.com –
Oxytocin [Internet].
Available from: https://www.medicinenet.com/oxytocin-injectable/article.htm#:~:text=Oxytocin%20works%20by%20increasing%20the,increases%20contraction%20of%20the%20uterus.
[cited 7/7/2020].

yourhormones.info –
Oxytocin [Internet].
Available from: https://www.yourhormones.info/hormones/oxytocin/
[cited 7/7/2020].
2015