Pelaroka ? contains an herbal extract, derived from the plant Pelargonium sidoides (P.s.).Each 120ml contains 319mg Pelargonium Sidoides extract.?Pelaroka has been evaluated for the management of upper respiratory tract symptoms. Pelaroka is used for the treatment of acute respiratory tract infections (ARls) where antibiotic use is unnecessary. It?s clinically proven to shorten the duration and reduce the severity of cough, congestion, sore throat, and nasal and bronchial irritations and it?s suitable for the
whole family (over 6 years).

In-vitro studies have found that it exerts a cytoprotective effect against virus-induced cell destruction and also increases the release of antimicrobial peptides (also known as defensins) from neutrophilic granulocytes. Studies have also found that P.S. acts as an immune stimulant. These actions are mediated mainly by the release of tumor necrosis factor (TNF-a) and nitric oxide, stimulation of interferon-b synthesis, and increase of natural killer cell activity. Studies have also found that P.S. increases phagocytosis.
Therapeutic Fields? of Pelaroka

Acute bronchitis, sinusitis and COPD
Common cold
Upper respiratory tract infections

Dosing and Administration

Adults and children over 12 years:

7.5 ml three times daily with or without food

Children aged 6 ? 12 years:

5ml three times daily with or without food Should be shaken well before use.
Contraindications of Pelaroka

Hypersensitivity to P.S. or any component of the formulation.
Pregnancy and Breastfeeding.
Diseases of the immune system (e.g. MS, SLE, RA).
Bleeding disorders.
Phenylketonuria.

Precautions

Use with caution in diabetic patients; concomitant use with antidiabetic agents

may cause hypoglycemia.
Use with caution in patients with bleeding disorders; concomitant use with

anticoagulant medications and antiplatelet drugs may cause increased bleeding risk.
Use with caution in patients with immune system diseases; concomitant use with immunosuppressant medications may reduce the therapeutic effect.

Drug Interactions

Some medications that decrease the immune system include azathioprine, basiliximab, cyclosporine, daclizumab, muromonab-CD3, mycophenolate, tacrolimus, sirolimus, prednisone, corticosteroids, and others.
An interaction may be possible when patients receive anticoagulant medications (e.g. warfarin) and antiplatelet drugs (e.g. aspirin).

Side-Effects of Pelaroka
(? 0.01 %): P.S. is likely safe when taken for up to 2 weeks. Some people who take it can experience stomach upset, and some might have an allergic reaction.