It works by inhibiting the binding of histamine to its receptor and thus helps in relieving the symptoms.
Side effects
Major & minor side effects for Phenergan Elixir 5 mg/5 mL 120 mL

Drowsiness severe

Headache severe

Seizures severe

Tremors severe

Skin rash

Loss of strength

Increased sensitivity of the skin to sunlight

Excitation

Uses of Phenergan Elixir 5 mg/5 mL 120 mL
What is it prescribed for?

Allergic reactions
Phenergan Elixir 5 mg/5 mL 120 mL is used to treat mild to moderate allergic reactions like urticaria, rhinitis.

Sedation
Phenergan Elixir 5 mg/5 mL 120 mL is used for preoperative, postoperative, and obstetric (during labor) sedation.

Nausea and vomiting
Phenergan Elixir 5 mg/5 mL 120 mL is used to prevent nausea and vomiting in postoperative patients.

Motion sickness
Phenergan Elixir 5 mg/5 mL 120 mL is used to relieve symptoms of motion sickness like nausea and vomiting.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed in 20 minutes after an oral dose and 3 to 5 minutes after an intravenous dose.

Duration of Effect
The effect of this medicine lasts for an average duration of 12 hours.

Safe with Alchohol?
Consumption of alcohol is not recommended if the patient is receiving Phenergan Elixir 5 mg/5 mL 120 mL . Any symptoms of dizziness, difficulty in concentration should be reported to the doctor. Do not perform activities that require mental alertness. An alternate medicine should be considered based on the clinical condition.

Is it habit forming?
No habit forming tendencies has been reported.

Usage in pregnancy?
This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?
This medicine is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Monitoring of symptoms like excessive sedation and irritability is necessary while breastfeeding.

When not to use?

Allergy
Not recommended in patients with known allergy to Phenergan Elixir 5 mg/5 mL 120 mL .

Asthma
Not recommended in patients with the history of asthma or any respiratory disease.

Central nervous system depression
Not recommended in patients with the history of central nervous system depression.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding
This medicine is not recommended in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Monitoring of symptoms like excessive sedation and irritability is necessary while breastfeeding.

General Warnings

Drowsiness
Phenergan Elixir 5 mg/5 mL 120 mL should be used with caution due to the risk of drowsiness. Do not perform activities that require mental alertness like driving vehicle and operating machinery. It is advised to take this medicine at bedtime.

Seizures
Phenergan Elixir 5 mg/5 mL 120 mL may lower the seizure threshold. It is used with caution in patients receiving medicines like narcotics or local anesthetic. Any symptoms of seizures should be informed to the doctor. Do not perform activities that require mental alertness like driving vehicle and operating machinery

Dosage

Missed Dose
The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of overdose.

Interactions
Interaction with Medicines

Escitalopram severe

Tramadol severe

Antidiabetic medicines moderate

Antihypertensives moderate

Disease interactions

severe
Inform the doctor if you have any respiratory disease. This medicine is not recommended due to the risk of respiratory depression. Any symptoms of breathing difficulty should be informed to the doctor.

severe
Inform the doctor if you have any central nervous system disorder or head injury. This medicine is not recommended due to the risk of central nervous system depression. Do not perform activities that require mental alertness.

Lab interactions

General Instructions

Take Phenergan Elixir 5 mg/5 mL 120 mL as advised by the doctor. Do not take larger amounts that prescribed. Any symptoms like dizziness and difficulty in concentration should be reported to the doctor. Do not perform activities that require mental alertness like driving vehicle and operating machinery.

Other details

To be taken before food

To be taken at bedtime only

Causes sleepiness

References

practo.com –
Promethazine [Internet].
Available from: https://www.practo.com/medicine-info/promethazine-232-api
[cited 20 september 2019].
5 Jan 2018

medlineplus.gov –
Promethazine [Internet].
Available from: https://medlineplus.gov/druginfo/meds/a682284.html
[cited 20 september 2019].
11 September 2019

.medicines.org.uk –
Promethazine [Internet].
Available from: https://www.medicines.org.uk/emc/medicine/21162
[cited 20 september 2019].
15 May 2018