Procarbizole tablet 50 mg 100?s (Propylthiouracil) works by stopping the thyroid gland from making thyroid hormone.
Side effects
Major & minor side effects for Procarbizole tablet 50 mg 100?s (Propylthiouracil)

Black or Tarry stools

Chest pain

Difficulty or painful urination

Shortness of breath

Dark colored urine

Stomach pain

Yellow colored eyes or skin severe

Weakness and general discomfort

Hair loss

Uses of Procarbizole tablet 50 mg 100?s (Propylthiouracil)
What is it prescribed for?

Hyperthyroidism
This medicine is used for the treatment of hyperthyroidism, an increase of thyroid hormone levels in the blood. It is also used to relieve the symptoms of hyperthyroidism before thyroid surgery or radioactive iodine treatment.

Graves Disease
This medicine is used for the treatment of Graves’ disease, an autoimmune disease where the thyroid gland produces an excessive amount of thyroid hormones and the main cause for hyperthyroidism.

Concerns

Frequently asked questions

Onset of action
The amount of time required for this medicine to show its action is not clinically established.

Duration of Effect
The effect of this medicine lasts for a maximum duration of 12-24 hours.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit forming tendency has been reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Procarbizole tablet 50 mg 100?s (Propylthiouracil) or any other inactive ingredients present along with it.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

General Warnings

Hepatotoxicity
This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of hepatotoxicity. Close monitoring of liver function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypothyroidism
This medicine should be used with caution due to the increased risk of hypothyroidism (low thyroid hormone levels). This risk is especially higher if the medicine is used for a prolonged period of time. Close monitoring of thyroid function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Agranulocytosis
This medicine should be used with extreme caution in patients suffering from agranulocytosis, a condition that affects white blood cells, since it may worsen the patient’s condition. Report to the doctor if you experience any unusual symptoms like fever, sore throat, shortness of breath, tiredness, pale skin, etc. immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Bleeding Disorders
This medicine should be used with extreme caution in patients suffering from bleeding disorders due to the increased risk of worsening of the patient’s condition. Close monitoring of prothrombin time/INR is necessary while taking this medicine. Appropriate dose adjustment or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Dosage

Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Leflunomide severe

Metoprolol moderate

Fluphenazine severe

Efavirenz moderate

Carvedilol moderate

Disease interactions

severe
This medicine should be used with caution in patients suffering from blood dyscrasias (Thrombocytopenia, Neutropenia, leukopenia, etc.) since it may worsen the patient’s condition. Regular monitoring of complete blood count levels is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

severe
This medicine should be used with caution in patients suffering from liver diseases or hepatitis due to the increased risk of hepatotoxicity. Close monitoring of liver functions tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

References

medlineplus.gov –
Propylthiouracil [Internet].
Available from: https://medlineplus.gov/druginfo/meds/a682465.html
[cited 4/9/2020].
2020