Qosmet tablet 50/1000 mg 10?s works to competitively inhibit the enzyme dipeptidyl peptidase 4 (DPP-4). This enzyme breaks down the incretins GLP-1 and GIP, gastrointestinal hormones released in response to a meal.[19] By preventing breakdown of GLP-1 and GIP, they are able to increase the secretion of insulin and suppress the release of glucagon by the alpha cells of the pancreas. This drives blood glucose levels towards normal. As the blood glucose level approaches normal, the amounts of insulin released and glucagon suppressed diminishes, thus tending to prevent an “overshoot” and subsequent low blood sugar (hypoglycemia), which is seen with some other oral hypoglycemic agents.
Concerns

Frequently asked questions

Onset of action

Duration of Effect

Safe with Alchohol?

Is it habit forming?

Usage in pregnancy?

Usage while breast-feeding?

Dosage

Missed Dose

Overdose

References

drugs.com –
Metformin and sitagliptin [Internet].
Available from: https://www.drugs.com/mtm/metformin-and-sitagliptin.html
[cited 30/6/2020].
9/4/2020

wikipedia –
Mechanism of action [Internet].
Available from: https://en.wikipedia.org/wiki/Sitagliptin#Mechanism_of_action
[cited 30/6/2020].
19/6/2020