RELIDEP 75mg Tablet 10?s Allschoolabs -

Description

INTRODUCTION
RELIDEP 75MG TABLET contains Amitriptyline which belongs to the group of medicines called Antidepressants. It is used to treat depression. It is also used to treat neuropathic pain and prevents chronic headache and migraine.
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest which affects how you feel, think or behave that leads to a variety of emotional and physical problems in the affected person.
Using RELIDEP 75MG TABLET should not be stopped suddenly, your physician may advise you to reduce dose gradually to overcome withdrawal symptoms.
RELIDEP 75MG TABLET is not recommended for use in patients suffering from mania and or having heart problems such as heart attack, disturbances in heart rhythm, heart block or coronary artery disease, irregular heartbeat and or congestive heart failure and severe liver disease.
Before taking RELIDEP 75MG TABLET, inform your doctor if you are suffering from epilepsy (seizures), depression, severe low blood pressure, bipolar disorder, urinary retention and or kidney problems.
RELIDEP 75MG TABLET is not recommended for use in pregnant women during first and third trimester period and breastfeeding women. It is also not recommended for children and adolescents (below 18 years). Consult your doctor before taking the medicine.
The most common side effects of taking RELIDEP 75MG TABLET are weight gain, gastrointestinal symptoms like constipation, sleepiness, drowsiness, dizziness, headache, dry mouth, slurred or slow speech. Consult your doctor if any of these above symptoms gets worse.
USES OF RELIDEP 75MG TABLET
It is used to treat:
Depression

Neuropathic pain

Chronic headache and migraine

HOW RELIDEP 75MG TABLET WORKS
RELIDEP 75MG TABLET prevents the reuptake and hence the inactivation of neurotransmitters noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain due to damaged nerves.
DIRECTIONS FOR USE
Take RELIDEP 75MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF RELIDEP 75MG TABLET

COMMON

Sleepiness ?

Shakiness of hands or other parts of the body

Dizziness

Headache

Irregular, hard or rapid heartbeat

Dry mouth

Constipation

Nausea

Excessive sweating

Weight gain

Slurred or slow speech

Aggression

Problem with ability of the eye to change its focus from distant to near objects (and vice versa)

Congested nose

Confusion

Sexual disturbances (problems with erection, decreased sex-drive)

Changes in taste

Numbness or tingling in the legs or arms

Signs of low sodium concentration in blood such as nausea, vomiting, headache and confusion

Urination disorder

Feeling thirsty

Agitation

Disturbed coordination

Dilated pupils

UNCOMMON

Excitement, anxiety, difficulties sleeping, nightmares

Convulsions

Tinnitus (ringing in ears)

Increased blood pressure

Skin rash, nettle rash (urticaria), swelling of the face and tongue

Difficulties passing urine

Breast milk outflow without breast feeding or increased production of breast milk

Collapse conditions

Liver function impairment such as cholestatic liver disease

RARE

Decreased appetite

Delirium (especially in elderly patients), hallucinations

Swelling of the salivary glands

Hair loss

Increased sensitivity to sunlight

Breast enlargement (men)

Fever

Weight loss

Abnormal results of liver function tests
Stop taking RELIDEP 75MG TABLET and contact your doctor immediately if you experience any of the following side effects:
Signs of a severe allergic reactions such as difficulty breathing or swelling of your face, lips, throat or tongue

Signs of acute glaucoma (eye disorder) such as attacks of intermittent blurring of vision, rainbow vision and eye pain

Irregular heart rhythm

Signs of paralyzed intestine such as bad constipation, a swollen stomach, fever and vomiting

Yellowing of the skin and the white in the eyes

Signs of blood or bone marrow being affected with symptoms such as bruising, bleeding, pallor or persistent sore throat and fever

Self-harming thoughts

HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and relax. Drink plenty of fluids such as water abnormal. Apply a pain-relieving balm on the head if required. Do not consume alcohol. Consult your doctor if the symptom did not improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhoea. Consult your doctor if the symptom did not improve.
Nausea or Vomiting:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if the symptom did not improve.
Constipation:
Eat more fiber especially soluble fiber foods like beans, oats, oat bran, rice bran, barley, citrus fruits, apples, strawberries. Keep yourself hydrated. Avoid taking any medicine on your own for treating constipation. Consult your doctor if the symptom did not improve.
Dizziness:
If you feel dizzy, keep your eyes closed sit or lie down. Do not drive or operate machinery. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS

PREGNANCY
RELIDEP 75MG TABLET is not recommended for use in pregnant women during first and third trimester. Consult your doctor before taking it.
BREASTFEEDING
RELIDEP 75MG TABLET is not recommended for use in breastfeeding women unless it is clearly necessary. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel drowsiness and dizziness after taking RELIDEP 75MG TABLET.
ALCOHOL
Avoid consumption of alcohol while taking RELIDEP 75MG TABLET because it might increase the sedative effects.
KIDNEY
[GNBKEYWORD] should be used with caution in patients with chronic renal failure. Consult your doctor before taking RELIDEP 75MG TABLET.
LIVER
RELIDEP 75MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild to moderate liver diseases. Consult your doctor before taking.
ALLERGY
Do not take RELIDEP 75MG TABLET if you are allergic to Amitriptyline, other tricyclic antidepressants or to any of the other ingredients of this medicine.
HEART DISEASE
RELIDEP 75MG TABLET is not recommended for use in patients with heart problems such as heart attack (myocardial infarction), disturbances in heart rhythm, heart block or coronary artery disease, irregular heartbeat and congestive heart failure. Consult your doctor before taking.
OTHERS
RELIDEP 75MG TABLET is not recommended for use if you:
Are suffering from mania
Before taking RELIDEP 75MG TABLET, inform your doctor if you have:
Epilepsy

Depression or anxiety

Porphyria (blood disorder)

Pheochromocytoma (tumor of the adrenal gland)

Blood dyscrasias (blood disorder)

Urinary retention

Prostatic hypertrophy (enlarged prostate) such as frequent or urgent need to urinate, increased frequency of urination at night and difficulty while urinating

Increased intra-ocular pressure or narrow angle glaucoma

Signs of hyperthyroidism (overactive thyroid) such as unintentional weight loss, increased appetite, nervousness

Severe low blood pressure

Planned for surgery

Signs of hyponatremia (low sodium level in blood) such as nausea, vomiting, headache., confusion

Difficulty in passing urine

Thyroid disease

Bipolar disorder

Schizophrenia (serious mental disorder)

Narrowing of the gastric outlet (pylorus stenosis) and blocked intestine (paralytic ileus)

Diabetes
Use in pediatrics:
RELIDEP 75MG TABLET is not recommended for use in children and adolescents below 18 years of age. Consult your doctor before taking the medicine.
Use in geriatrics:
RELIDEP 75MG TABLET should be used with caution in elderly aged above 65 years. Consult your doctor before taking the medicine.
INTERACTIONS
A. Drug ? Drug interactions:
Before taking RELIDEP 75MG TABLET, inform your doctor if you are taking:
Medicines used to treat depression. Ex. phenelzine, iproniazid, isocarboxazid, nialamide, tranylcypromine, paroxetine, fluoxetine, fluvoxamine, duloxetine, bupropion

Selegiline (used to treat Parkinson?s disease)

Adrenaline, ephedrine, isoprenaline, noradrenaline, phenylephrine and phenylpropanolamine (used as anesthetics)

Calcium-channel blockers (used to treat high blood pressure) Ex. verapamil and diltiazem

Guanethidine, betanidine, clonidine, reserpine and methyldopa (medicines used in the treatment of high blood pressure)

Anticholinergic drugs (used to treat Parkinson?s disease and gastrointestinal disorders) Ex. atropine, hyoscyamine

Thioridazine (used in the treat schizophrenia)

Nefopam, tramadol and morphine (used to reduce pain)

Medicines to treat fungal infections (Ex. fluconazole, terbinafine, ketoconazole and itraconazole)

Sedatives (used in treatment of pain) such as barbiturates Ex. amobarbital, butabarbital?

Buprenorphine / opioids (used for severe pain or opioid drug addiction)

Medicines used to treat diseases associated with heart such as beta blockers (Ex. acebutolol, atenolol) and antiarrhythmics (Ex. disopyramide, flecainide)

Cimetidine (used to treat stomach ulcers)

Alpha2-adrenoceptor stimulants used to treat attention-deficit/hyperactivity disorder Ex. methylphenidate

Ritonavir (used to treat HIV)

Oral contraceptives (used to inhibit pregnancy) Ex. estrogens and progestogens

Rifampicin (to treat bacterial infections)

Phenytoin and carbamazepine (used to treat epilepsy)

St. john?s wort (herbal medicine used to treat depression)

Thyroid medication (used to abnormal thyroid) Ex. thyroxine

Medicines to treat irregular heartbeats (Ex. quinidine and sotalol)

Astemizole and terfenadine (used to treat allergies and hay fever)

Medicines used to treat mental illnesses Ex. pimozide and sertindole

Cisapride (used to treat certain types of indigestion)

Halofantrine (used to treat malaria)

Methadone (used as detoxicant and to treat pain)

Diuretics (used to treat hypertension) Ex. furosemide

Altretamine (used to treat cancer of the ovaries)

Disulfiram (used to treat chronic alcoholism)

Dopaminergics (used to treat Parkinson?s disease and restless legs syndrome)

Baclofen (used as muscle relaxant)

Nitrate medicine (used to treat angina) Ex. glyceryl trinitrate

Sibutramine (used as an anti-obesity medicine)
Over dosage:
If you or anyone else accidentally takes too much of RELIDEP 75MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include dilated pupils, fast or irregular heartbeats, dry mouth and tongue, fever, agitation, difficulty breathing, blue discoloration of the skin, confusion, hallucinations, disturbed concentration, fast heartrate, uncontrolled movements, difficulties passing water, intestinal blockage, fits, low blood pressure, weak pulse, pallor, decreased heart rate, drowsiness, impaired conduction of heart, hypokalemia, drowsiness, hypothermia, hyperactive reflexes, muscle rigidity and vomiting.
SYNOPSIS

Drug :?? Amitriptyline

Pharmacological Category :?? Anti-depressants

Therapeutic Indication :?? Depression, Neuropathic pain, Migraine???????????

Dosage Forms :?? Tablet

MORE INFORMATION

Keep RELIDEP 75MG TABLET out of reach of children

Store below 25?C

FAQs ABOUT RELIDEP 75MG TABLET
Can RELIDEP 75MG TABLET make you more depressed after a while or make your condition worse?
Taking RELIDEP 75MG TABLET can?t make your mood worse. But it may have side effects that can change or alter your mood. Consult your doctor if you get any extreme thoughts, mood swings or unusual changes in behavior in the first weeks after taking RELIDEP 75MG TABLET.
How much dose of RELIDEP 75MG TABLET can I take in a day?
Take RELIDEP 75MG TABLET as advised by your physician. Do not crush or chew the medicine. Swallow the medicine with glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Is RELIDEP 75MG TABLET an antibiotic?
No, RELIDEP 75MG TABLET is not an antibiotic. RELIDEP 75MG TABLET belongs to group of medicines called antidepressants which is used to treat major depressive episodes of depression and neuropathic pain in adults which is also used to prevent chronic headache and migraine.
Can I consume alcohol after taking RELIDEP 75MG TABLET?
Sleepiness or drowsiness is the common side effect of RELIDEP 75MG TABLET. Since alcohol has sedative effect or it induces sleep, alcohol is not recommended for use after taking RELIDEP 75MG TABLET.
Can RELIDEP 75MG TABLET be used in pregnancy?
RELIDEP 75MG TABLET is not recommended for use in pregnancy during first and third trimester. Stop taking this medicine if you become pregnant. Consult your doctor before taking RELIDEP 75MG TABLET.
REFERENCES
1. K.D. Tripathi. Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs. Essentials of medical pharmacology. Seventh edition. 2013 Page 455.
2. Amit Thour, Raman Marwaha. Amitriptyline. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls. [Revised on May 2022] [Accessed on 26th April 2022]?https://www.ncbi.nlm.nih.gov/books/NBK537225/
3.?M Sandoz,?S Vandel,?B Vandel,?B Bonin,?B Hory,?Y St Hillier,?R Volmat. Metabolism of amitriptyline in patients with chronic renal failure. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised on 1984] [Accessed on 26th April 2022] https://pubmed.ncbi.nlm.nih.gov/6723762/
4. DOUGLAS M. MAURER; TYLER J. RAYMOND; and BETHANY N. DAVIS. Depression: Screening and Diagnosis, American Family Physician Organization. [Revised Oct 2018] [Accessed on 26th April 2022]?https://www.aafp.org/afp/2018/1015/p508.htm
5.?Pharmascience INC. Drug and Health Product Register [Revised Sep 2017] [Accessed on 26th April 2022]?https://pdf.hres.ca/dpd_pm/00041275.PDF
6. Sandoz INC. Food and Drugs Administration (FDA) [Revised May 2014] [Accessed on 26th April 2022]?https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/085966s095,085969s084,085968s096,085971s075,085967s076,085970s072lbl.pdf
7. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC) [Revised Jan 2022] [Accessed on 26th April 2022]?https://www.medicines.org.uk/emc/files/pil.10849.pdf
PRODUCT DETAILS