Spike tablet 200 mg 10?s works by stopping the growth of the fungus.
Side effects
Major & minor side effects for Spike tablet 200 mg 10?s

Blurred vision severe

Chest pain severe

Dizziness severe

Fast heartbeat severe

Increased sensitivity of the eyes to sunlight severe

Yellow colored eyes or skin severe

Joint pain severe

Diarrhea rare

Hair loss or thinning of the hair rare

Nausea and Vomiting rarerare

Loss of appetite rare

Uses of Spike tablet 200 mg 10?s
What is it prescribed for?

Blastomycosis
This medicine is used in the treatment of blastomycosis, which is a fungal infection that can affect skin, bones, and joints caused by the fungus Blastomyces dermatitidis.

Chromomycosis
This medicine is used in the treatment of Chromomycosis, which is a fungal infection that can affect the skin and subcutaneous tissue caused by Fonsecaea pedrosoi, Phialophora verrucosa, etc.

Coccidioidomycosis
This medicine is used in the treatment of Coccidioidomycosis, which is a fungal infection caused by Coccidioides. This infection can affect the lungs and other parts of the body.

Histoplasmosis
This medicine is used in the treatment of Histoplasmosis, which is a fungal infection caused by Histoplasma capsulatum. This infection can affect the lungs and other parts of the body.

Paracoccidioidomycosis
This medicine is used in the treatment of Paracoccidioidomycosis, which is a fungal infection caused by Paracoccidioides brasiliensis. This infection can affect the lungs and other parts of the body.

Concerns

Frequently asked questions

Onset of action
The effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.

Safe with Alchohol?
Consumption of alcohol is not recommended while you are taking this medicine due to the increased risk of adverse effects such as sweating, headache, flushing, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.

Is it habit forming?
No habit-forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Spike tablet 200 mg 10?s or any other inactive ingredients present in the formulation.

QT Interval prolonging drugs
This medicine is not recommended for co-administration with drugs like dofetilide, pimozide, quinidine, and cisapride that are known to cause elevated plasma concentrations of this medicine and may prolong the QT interval.

Liver Disease
This medicine is not recommended for use in patients with acute or chronic liver diseases due to the increased risk of worsening of the patient’s condition.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

General Warnings

Liver Disease
This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT prolongation
This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals due to the increased risk of worsening of the patient’s condition. Replacement with a suitable alternative should be considered in some cases based on the clinical condition.

Kidney disease
This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in Children
This medicine is not recommended for use in children below 2 years of age since the safety and efficacy of use are not clinically established.

Adrenal insufficiency
Use of this medicine at high doses may decrease the adrenal corticosteroid secretion and hence caution is advised in patients with adrenal insufficiency. The recommended dose should not exceed 400 mg. Close monitoring of adrenal function, appropriate dose adjustment, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or Operating machinery
Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose
Seek emergency medical treatment or contact your doctor in case of an overdose.

Interactions
Interaction with Medicines

Alprazolam severe

Cisapride severe

Erythromycin severe

Warfarin moderate

Atorvastatin severe

Ceritinib severe

Disease interactions

severe
This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

moderate
This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs. This medicine may further prolong QT intervals in such patients and worsen the patient’s condition. Replacement with a suitable alternative should be considered in some cases based on the clinical condition.

moderate
This medicine should be used with caution in patients with adrenal insufficiency due to the increased risk of worsening of the patient’s condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

General Instructions

Take this medicine with or without food, as directed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Other details

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

References

webmd.com –
Ketoconazole [Internet].
Available from: https://www.webmd.com/drugs/2/drug-11593/ketoconazole-oral/details
[cited 7/7/2020].