Acetazolamide 250mg (Single Tablets)
Acetazolamide also known as Diamox is a carbonic anhydrase inhibitor. licenced for the treatment of glaucoma,? fluid retention and epilepsy.? Like many online doctor services and high altitude medicine specialists, we prescribe this medicine off-label for the prevention of altitude sickness in travellers ascending to altitudes over 2500m.? Patient information leaflets issued with this medicine will not provide advice about the use of this medicine for Altitude sickness. This medicine is usually effective for speeding up the acclimatisation process, but importantly it is still possible to develop symptoms of acute mountain sickness (AMS), pulmonary oedema (HAPE) or cerebral oedema (HACE) whilst taking this medicine.? Slow ascents are the key to safe travel to high-altitude destinations, but Acetazolamide can help. Acetazolamide works to counter the effect of lower oxygen pressure in high altitude regions.? As you ascend oxygen pressure drops, which means you absorb less oxygen with each intake of air to your lungs.? Acetazolamide removes Bicarbonate from your body, increasing the acidity of your blood (known as metabolic acidosis).? This change to blood pH triggers a slightly increased respiratory rate, which in turn increases the amount of oxygen you intake over time. Other medicines can be used for the prevention of AMS, HAPE or HACE but Acetazolamide was shown in trials to be one of the most effective.? If Acetazolamide is unsuitable for you our specialist may be able to offer you an alternative.
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