CIPRODIAZOLE 500 / 500 MG ( CIPROFLOXACIN /?METRONIDAZOLE )?20 FILM-COATED?TABLETS

Ciprodiazole the optimal alliance combating mixed infections. Ciprodiazole is the first and only Ciprofloxacin/ Metronidazole combination in the Egyptian market. It is indicated for all types of mixed infections and recommended by international guidelines.

Ingredient:

Ciprofloxacin 500mg/ Metronidazole 500mg

Insert leaflet

Composition: Each film coated tablet contains: Ciprofloxacin hydrochloride monohydrate 524.35 mg Eq. to Ciprofloxacin hydrochloride 500 mg Metronidazole 500 mg.

Excipients: pregelatinized starch, sodium starch glycolate, P.V.P K 30, lactose monohydrate 200 mesh, sodium lauryl sulphate, magnesium stearate, wincoat green.

Indications: It is used in the treatment of Intra-abdominal and pelvic infections caused by E. coil, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumonia, or Bacteroides fragilis . Diverticulitis.

Dose: The recommended dosage is 1 tablet taken every 12 hours.

Contraindicated:

1- It is contraindicated in patients who are hypersensitive to Ciprofloxadn or other antibiotics of Quinolones group such as Orfloxacin, Norfloxacin, Trovofloxacin, Ofloxacin, as an allergic reaction may occur.

2- It is contraindicated with drugs primarily metabolized by CYP1A2 (cytochrome-1A2).

3- It is contraindicated with administration of Tizanidine.

4- It is contraindicated in patients with epilepsy or other seizure disorders.

5- It is contraindicated in children & adolescents below 16 years.

6- It is contraindicated in patients who are hypersensitive to the metronidazole or other nitroimidazole derivatives, as an allergic reaction may occur.

7- Metronidazole should not be administered to patients with active neurological disorders or a history of blood dyscrasias. 8- Ills contraindicated in patents with G 6 PD enzyme deficiency.