Rifampicin capsule 300 mg 8?s works by interfering with the bacterial DNA synthesis and stops the growth of the bacteria.
Side effects
Major & minor side effects for Rifampicin capsule 300 mg 8?s

Abdominal pain severe

Dizziness severe

Headache severe

Yellow colored eyes or skin severe

Nausea and Vomiting severe

Skin rash severe

Loss of appetite severe

Unusual behavior rare

Muscle pain rare

Weakness rare

Swelling of face, lips, eyelids, tongue, hands and feet rare

Chest pain

Irregular heartbeat rare

Uses of Rifampicin capsule 300 mg 8?s
What is it prescribed for?

Tuberculosis
Rifampicin capsule 300 mg 8?s is used in the treatment of tuberculosis which is a lung infection caused by Mycobacterium tuberculosis.

Meningococcal Meningitis
Rifampicin capsule 300 mg 8?s is used in the treatment of meningococcal meningitis which is an infection that affects the brain and spinal cord caused by Neisseria meningitidis.

Leprosy
This medicine is used in combination with other medicines in the treatment of leprosy which is a bacterial infection which is characterized by skin ulcers, nerve damage, and muscle weakness, etc.

Concerns

Frequently asked questions

Onset of action
The peak effect of this medicine can be observed in 2 to 4 hours.

Duration of Effect
The effect of this medicine lasts for an average duration of 9 to 12 hours.

Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?
No habit forming tendencies were reported.

Usage in pregnancy?
This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Usage while breast-feeding?
This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.

When not to use?

Allergy
Not recommended in patients with known allergy to [post_titlte].

Antiviral medications
Not recommended in patients receiving antiviral therapy due to the decrease in the effect of antiviral medications.

Warnings

Warnings for special population

Pregnancy
This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Breast-feeding
This medicine is excreted in breast milk. It is recommended for breastfeeding women only if clearly needed. The risk and benefits should be discussed with the doctor before taking this medicine.

General Warnings

Liver injury
This medicine may cause liver injury, therefore should be used with caution. The liver function tests should be performed before starting the treatment. The dose should be adjusted based on the severity of liver disease.

Diabetes
This medicine may alter the blood glucose levels. Inform the doctor about your medical condition before starting the treatment. Monitoring of blood glucose levels is necessary.

Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Other uses
Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Dosage

Missed Dose
If you miss a dose of Rifampicin capsule 300 mg 8?s , take the missed dose as soon as you remember. If it?s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions
Interaction with Medicines

Clopidogrel moderate

Propranolol moderate

Warfarin severe

Atorvastatin severe

Live cholera vaccine severe

Diltiazem severe

Cyclosporine severe

Avanafil moderate

Disease interactions

severe
Inform the doctor if you have liver disease before receiving this medicine. Close monitoring of liver function is necessary. Any signs of an increase in the liver enzymes should be informed to the doctor. The treatment should be stopped temporarily until the liver enzymes return to normal.

severe
This medicine should be used with caution in patients with a history of colitis due to the increased risk of worsening the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative might be required in some cases based on the clinical condition.

severe
This medicine should be used with extreme caution in patients with preexisting bone marrow depression or blood dyscrasias due to the increased risk of serious hematopoietic abnormalities. These abnormalities may include thrombocytopenia, leukopenia, decreased hemoglobin levels, acute hemolytic anemia, etc. Close monitoring of complete blood counts, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Lab interactions

General Instructions

Take Rifampicin capsule 300 mg 8?s as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Do not stop taking the medicine without consulting your doctor. Ensure that the course of treatment is completed to prevent the spread of infection. Consult the doctor if you experience any undesirable effects

Other details

To be taken before food

To be taken as instructed by doctor

Does not cause sleepiness

References

practo.com –
Rifampicin [Internet].
Available from: https://www.practo.com/medicine-info/rifampicin-339-api
[cited 19 september 2019].
5 Jan 2018

dailymed.nlm.nih.gov –
Rifampicin [Internet].
Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=55816042-946d-4bec-9461-bd998628ff45
[cited 19 september 2019].
April 1, 2019